IFI27

Name	interferon alpha inducible protein 27
Structure	No pdb structure
Novel Interactors	1 novel interactors: CKB
Interactors	4 interactors: APOC2 APOC4 CCND1 CDK4
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Lamin Binding Identical Protein Binding Molecular Adaptor Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Immune System Process Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Host-mediated Perturbation Of Viral Genome Replication Innate Immune Response Regulation Of Protein Export From Nucleus Defense Response To Virus Type I Interferon-mediated Signaling Pathway Pyroptotic Inflammatory Response Protein K48-linked Ubiquitination Extrinsic Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway
Pathways	Interferon alpha/beta signaling Modulation of host responses by IFN-stimulated genes
GWAS	No GWAS studies recorded
Entrez ID	3429
HPRD ID	02479
Ensembl ID	ENSG00000165949
Uniprot IDs	P40305
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Cyclin D1-CDK4 Complex High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Positive Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Acylglycerol Homeostasis Triglyceride Homeostasis Cyclin-dependent Protein Kinase Holoenzyme Complex Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Kinase Activity Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Cyclin D1-CDK6 Complex Regulation Of G2/M Transition Of Mitotic Cell Cycle Bicellular Tight Junction Cyclin D3-CDK4 Complex Futile Creatine Cycle Positive Regulation Of Phospholipid Catabolic Process Lipoprotein Lipase Activator Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cyclin D2-CDK4 Complex Lipid Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remodeling Re-entry Into Mitotic Cell Cycle Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Intermediate-density Lipoprotein Particle Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Response To Ketone Cellular Response To Ionomycin Phosphocreatine Biosynthetic Process Creatine Kinase Activity Spherical High-density Lipoprotein Particle Positive Regulation Of Triglyceride Catabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Very-low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Clearance Positive Regulation Of Cell Cycle Process Response To Vitamin E Nuclear Membrane Response To Alcohol Triglyceride-rich Lipoprotein Particle Remodeling