HCFC2

Name	host cell factor C2
Structure	No pdb structure
Novel Interactors	2 novel interactors: CKAP4 COL6A1
Interactors	2 interactors: GRSF1 KMT2A
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Histone Methyltransferase Complex MLL1/2 Complex Set1C/COMPASS Complex MLL1 Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Viral Process Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of DNA-templated Transcription Antiviral Innate Immune Response Immune Response Involved In Response To Exogenous DsRNA
Pathways	Formation of WDR5-containing histone-modifying complexes
GWAS	PR interval ( 32439900 )
Entrez ID	29915
HPRD ID	06393
Ensembl ID	ENSG00000111727
Uniprot IDs	Q9Y5Z7
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Membrane Depolarization Response To Bleomycin Collagen Type VI Trimer Apoptotic Nuclear Changes Rhythmic Process Regulation Of Collagen Fibril Organization Skeletal Muscle Tissue Growth Limb Joint Morphogenesis Mitochondrial Depolarization Multicellular Organismal Locomotion Skeletal Muscle Fiber Differentiation Response To Polyamine Macromolecule Reduction Of Food Intake In Response To Dietary Excess Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Caveola Assembly Response To Light Stimulus Circadian Rhythm Homeostasis Of Number Of Cells Endoplasmic Reticulum Lumen Fat Cell Proliferation G-quadruplex RNA Binding Anterior/posterior Pattern Specification Mitochondrial RNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Regionalization T-helper 2 Cell Differentiation Unmethylated CpG Binding Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Protein-cysteine Methyltransferase Activity MLL1/2 Complex Negative Regulation Of Heterochromatin Formation Histone H3K4 Monomethyltransferase Activity Histone H3K4 Trimethyltransferase Activity Minor Groove Of Adenine-thymine-rich DNA Binding Regulation Of Heterochromatin Formation Lamellar Body Plasma Membrane Raft Assembly Nucleobase-containing Compound Catabolic Process Platelet-derived Growth Factor Binding Mitochondrion Membrane Raft Assembly Plasma Membrane Raft Organization Pattern Specification Process Regulation Of Short-term Neuronal Synaptic Plasticity Ribonucleoprotein Granule Histone H3K4 Methyltransferase Activity Regulation Of Membrane Potential Response To Radiation 2-oxoglutarate Metabolic Process Definitive Hemopoiesis