TSKU

Name	tsukushi, small leucine rich proteoglycan
Structure	No pdb structure
Interactors	1 interactors: SKIL
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Binding Transforming Growth Factor Beta Binding
	Biological Process	Growth Plate Cartilage Chondrocyte Development Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Nervous System Development Cholesterol Metabolic Process Anatomical Structure Morphogenesis Regulation Of Gene Expression Negative Regulation Of Neuron Projection Development Corpus Callosum Morphogenesis Lateral Ventricle Development Hippocampus Development Anterior Commissure Morphogenesis Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Cholesterol Efflux Wound Healing Cholesterol Homeostasis Positive Regulation Of Hair Cycle Camera-type Eye Development Inner Ear Receptor Cell Stereocilium Organization Ciliary Body Morphogenesis Energy Homeostasis Bone Growth Negative Regulation Of Myofibroblast Differentiation
GWAS	Adult body size ( 32376654 ) Asthma ( 31959851 ) Factor VII activity ( 30642921 ) Gastroesophageal reflux disease ( 34187846 )
Entrez ID	25987
HPRD ID	12152
Ensembl ID	ENSG00000182704
Uniprot IDs	B3KRF9 Q8WUA8
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Skeletal Muscle Tissue Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Lymphocyte Homeostasis Response To Antibiotic Lens Fiber Cell Differentiation Positive Regulation Of Axonogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Leukocyte Homeostasis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage SMAD Binding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Blastocyst Formation Positive Regulation Of Apoptotic Signaling Pathway Striated Muscle Tissue Development Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Muscle Structure Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Axonogenesis Muscle Tissue Development Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of BMP Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Acrosomal Vesicle Homeostasis Of Number Of Cells PML Body