ANAPC13

Name	anaphase promoting complex subunit 13
Structure
Novel Interactors	1 novel interactors: NPHP3
Interactors	1 interactors: CDC42
GO Annotations	Cellular Component	Nucleus Anaphase-promoting Complex
	Molecular Function	Protein Binding
	Biological Process	Regulation Of Mitotic Cell Cycle Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process Cell Division Regulation Of Meiotic Cell Cycle Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein Branched Polyubiquitination
Pathways	Antigen processing: Ubiquitination & Proteasome degradation
GWAS	Height ( 18391952 31562340 ) Neurocognitive impairment in HIV-1 infection (dichotomous) ( 28447399 ) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625 ) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500 ) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625 ) Waist circumference adjusted for BMI in active individuals ( 28448500 ) Waist circumference adjusted for BMI in non-smokers ( 28443625 ) Waist circumference adjusted for body mass index ( 25673412 28448500 )
Entrez ID	25847
HPRD ID	08531
Ensembl ID	ENSG00000129055
Uniprot IDs	A8K3Z6 Q9BS18
PDB IDs	4UI9 5G04 5KHR 5KHU 5L9T 5L9U 5LCW 6Q6G 6Q6H 6TLJ 6TM5 6TNT 8PKP 8TAR 8TAU 9GAW
GO Terms Enriched among Interactors ?	Wnt Signaling Pathway Apolipoprotein A-I Receptor Binding Cell Projection Assembly Endothelin Receptor Signaling Pathway Involved In Heart Process Tube Development Microtubule-based Transport Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Plasma Membrane Bounded Cell Projection Assembly Establishment Or Maintenance Of Cell Polarity Maintenance Of Animal Organ Identity Ciliary Inversin Compartment Determination Of Stomach Left/right Asymmetry Determination Of Intestine Left/right Asymmetry Microtubule-based Movement Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Ureter Development Determination Of Digestive Tract Left/right Asymmetry Determination Of Pancreatic Left/right Asymmetry Convergent Extension Involved In Gastrulation Determination Of Liver Left/right Asymmetry Establishment Of Golgi Localization Leading Edge Membrane Thioesterase Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Neuron Fate Determination Golgi Transport Complex Atrial Septum Development Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Golgi Localization Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Convergent Extension Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Kidney Morphogenesis Cardiac Conduction System Development Establishment Of Epithelial Cell Apical/basal Polarity Cell Migration Involved In Heart Development Dendritic Spine Morphogenesis Microtubule-based Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore Establishment Of Apical/basal Cell Polarity Dendritic Cell Migration Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction