SIGLEC11

Name	sialic acid binding Ig like lectin 11
Structure	No pdb structure
Interactors	3 interactors: LGALS3BP PTPN11 PTPN6
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Phosphatase Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Cell Adhesion
Pathways	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
GWAS	Lung cancer in never smokers ( 28604730 )
Entrez ID	114132
HPRD ID	06196
Ensembl ID	ENSG00000161640
Uniprot IDs	Q96RL6
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Neutrophil Activation Regulation Of Neutrophil Activation Neutrophil Activation Involved In Immune Response Peptidyl-tyrosine Dephosphorylation Platelet Formation Megakaryocyte Development Regulation Of Lipopolysaccharide-mediated Signaling Pathway Neutrophil Activation Regulation Of Type I Interferon-mediated Signaling Pathway Phosphotyrosine Residue Binding T Cell Costimulation Regulation Of Cell Adhesion Mediated By Integrin Myeloid Cell Development Negative Regulation Of T Cell Proliferation Protein Dephosphorylation Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Cell Adhesion Molecule Binding Protein Tyrosine Phosphatase Activity Negative Regulation Of Leukocyte Proliferation Dephosphorylation Myeloid Leukocyte Activation Epididymis Development Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Phosphoprotein Phosphatase Activity Negative Regulation Of T Cell Activation Leukocyte Activation Involved In Immune Response Negative Regulation Of Leukocyte Cell-cell Adhesion Cell Activation Involved In Immune Response Negative Regulation Of Lymphocyte Activation Regulation Of Tumor Necrosis Factor Production Hemopoiesis Regulation Of Cytokine-mediated Signaling Pathway Regulation Of T Cell Proliferation Intestinal Epithelial Cell Migration Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell-cell Adhesion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Cell Activation Cerebellar Cortex Formation Regulation Of Mononuclear Cell Proliferation Myeloid Cell Differentiation Positive Regulation Of T Cell Activation Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of Glucocorticoid Secretion Regulation Of Leukocyte Proliferation Regulation Of ERK1 And ERK2 Cascade CD27 Signaling Pathway