RAB31

Name	RAB31, member RAS oncogene family
Structure
Novel Interactors	1 novel interactors: IRAK1
Interactors	6 interactors: ALS2CL EEA1 EGFR MAPK6 MPP3 OCRL
GO Annotations	Cellular Component	Phagocytic Cup Cytoplasm Endosome Early Endosome Late Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane Early Phagosome Membrane Phagocytic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process	Intracellular Protein Transport Endocytosis Receptor Internalization Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Golgi Vesicle Transport Positive Regulation Of Phagocytosis, Engulfment Phagosome Maturation
Pathways	Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
GWAS	Age at first sexual intercourse ( 27089180 ) Basophil count ( 32888494 ) Blood pressure (age interaction) ( 24954895 ) Bone fracture in osteoporosis ( 28580392 ) Dupuytren's disease ( 28886342 ) Lung adenocarcinoma ( 28604730 )
Entrez ID	11031
HPRD ID	05751
Ensembl ID	ENSG00000168461
Uniprot IDs	Q13636
PDB IDs	2FG5
GO Terms Enriched among Interactors ?	Early Endosome Membrane MAPK Cascade Kinase Activity Protein Kinase Activity Epidermal Growth Factor Binding Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Shc-EGFR Complex Multivesicular Body, Internal Vesicle Lumen Inositol Phosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol Bisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Septin Cytoskeleton Postsynaptic Early Endosome Axonal Spine Chemical Synaptic Transmission, Postsynaptic Synaptic Vesicle To Endosome Fusion