TSPAN5

Name	tetraspanin 5
Structure	No pdb structure
Interactors	1 interactors: APP
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Lumen Plasma Membrane Membrane
	Molecular Function	Protein Binding Enzyme Binding
	Biological Process	Intracellular Protein Localization Positive Regulation Of Notch Signaling Pathway Regulation Of Membrane Protein Ectodomain Proteolysis Protein Maturation Protein Localization To Plasma Membrane
Pathways	Amyloid fiber formation
GWAS	Alcohol consumption ( 28937693 ) Alcohol consumption (drinks per week) ( 30643258 ) Alcohol use disorder ( 30940813 ) Daytime sleep phenotypes ( 27126917 ) Depressive episodes in bipolar disorder ( 26297903 ) Sensation seeking ( 30718321 ) Stroke ( 32693751 )
Entrez ID	10098
HPRD ID	15513
Ensembl ID	ENSG00000168785
Uniprot IDs	B7Z317 D6RAR1 P62079
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding