Search Results for: KMT2A

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit
  • Formation of the beta-catenin:TCF transactivating complex
  • PKMTs methylate histone lysines
  • Deactivation of the beta-catenin transactivating complex
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • Neddylation
  • Formation of WDR5-containing histone-modifying complexes
  • Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of PD-L1(CD274) transcription
  • Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome
RBM39 RNA binding motif protein 39
  • mRNA Splicing - Major Pathway
RDX radixin
  • Recycling pathway of L1
  • Recycling pathway of L1
  • Sensory processing of sound by inner hair cells of the cochlea
  • Sensory processing of sound by outer hair cells of the cochlea
  • 1D-myo-inositol 1,4,5-trisphosphate
RNF2 ring finger protein 2
  • Oxidative Stress Induced Senescence
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of transcription cofactors
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA methylation proteins
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Transcriptional Regulation by E2F6
SBF1 SET binding factor 1
  • Synthesis of PIPs at the ER membrane
  • RAB GEFs exchange GTP for GDP on RABs
SET SET nuclear proto-oncogene
  • Condensation of Prophase Chromosomes
  • HuR (ELAVL1) binds and stabilizes mRNA
SVIL supervillin
TAF9 TATA-box binding protein associated factor 9
  • HIV Transcription Initiation
  • RNA Polymerase II HIV Promoter Escape
  • Transcription of the HIV genome
  • HATs acetylate histones
  • RNA Polymerase II Pre-transcription Events
  • Regulation of TP53 Activity through Phosphorylation
  • RNA polymerase II transcribes snRNA genes
  • RNA polymerase II transcribes snRNA genes
  • RNA Polymerase II Promoter Escape
  • RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
  • RNA Polymerase II Transcription Initiation
  • RNA Polymerase II Transcription Initiation And Promoter Clearance
TASP1 taspase 1
  • Formation of WDR5-containing histone-modifying complexes
  • Formation of WDR5-containing histone-modifying complexes
TGFB2 transforming growth factor beta 2
  • Platelet degranulation
  • Molecules associated with elastic fibres
  • TGF-beta receptor signaling activates SMADs
  • ECM proteoglycans
  • TGFBR3 regulates TGF-beta signaling
  • Trabedersen
  • Graft-versus-host disease
  • Allograft rejection
VWA5A von Willebrand factor A domain containing 5A
WDR5 WD repeat domain 5
  • PKMTs methylate histone lysines
  • HATs acetylate histones
  • HATs acetylate histones
  • RMTs methylate histone arginines
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • Neddylation
  • Cardiogenesis
  • Formation of WDR5-containing histone-modifying complexes
  • Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of PD-L1(CD274) transcription
  • Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome

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