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H3C14 |
H3 clustered histone 14 |
- Interleukin-7 signaling
- Interleukin-7 signaling
- Pre-NOTCH Transcription and Translation
- Formation of the beta-catenin:TCF transactivating complex
- PRC2 methylates histones and DNA
- Condensation of Prophase Chromosomes
- Oxidative Stress Induced Senescence
- Senescence-Associated Secretory Phenotype (SASP)
- HDACs deacetylate histones
- PKMTs methylate histone lysines
- HDMs demethylate histones
- HATs acetylate histones
- HATs acetylate histones
- RMTs methylate histone arginines
- Chromatin modifying enzymes
- SIRT1 negatively regulates rRNA expression
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- NoRC negatively regulates rRNA expression
- NoRC negatively regulates rRNA expression
- B-WICH complex positively regulates rRNA expression
- DNA methylation
- Transcriptional regulation by small RNAs
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Assembly of the ORC complex at the origin of replication
- RNA Polymerase I Promoter Opening
- RNA Polymerase I Promoter Escape
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Estrogen-dependent gene expression
- Meiotic recombination
- HCMV Early Events
- HCMV Late Events
- Transcriptional regulation of granulopoiesis
- Defective pyroptosis
- Negative Regulation of CDH1 Gene Transcription
- Amyloid fiber formation
- Chromatin modifications during the maternal to zygotic transition (MZT)
- Factors involved in megakaryocyte development and platelet production
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- Regulation of endogenous retroelements by KRAB-ZFP proteins
- Regulation of endogenous retroelements by KRAB-ZFP proteins
- Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
- Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
- Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
- Regulation of PD-L1(CD274) transcription
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HCFC1 |
host cell factor C1 |
- Transcriptional activation of mitochondrial biogenesis
- HATs acetylate histones
- UCH proteinases
- Formation of WDR5-containing histone-modifying complexes
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HCFC2 |
host cell factor C2 |
- Formation of WDR5-containing histone-modifying complexes
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IL10RA |
interleukin 10 receptor subunit alpha |
- Interleukin-10 signaling
- Nuclear events stimulated by ALK signaling in cancer
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INPPL1 |
inositol polyphosphate phosphatase like 1 |
- Synthesis of PIPs at the plasma membrane
- Synthesis of IP3 and IP4 in the cytosol
- Interleukin receptor SHC signaling
- Signaling by CSF1 (M-CSF) in myeloid cells
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INS |
insulin |
- Regulation of gene expression in beta cells
- Insulin processing
- Insulin processing
- Synthesis, secretion, and deacylation of Ghrelin
- Regulation of insulin secretion
- COPI-mediated anterograde transport
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- IRS activation
- Signal attenuation
- Insulin receptor signalling cascade
- Signaling by Insulin receptor
- Insulin receptor recycling
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- NPAS4 regulates expression of target genes
- Amyloid fiber formation
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- Glisoxepide
- Zinc
- M-Cresol
- Myristic acid
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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- Permanent neonatal diabetes mellitus (PNDM)
- Type I diabetes mellitus
- Maturity onset diabetes of the young (MODY)
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KAT8 |
lysine acetyltransferase 8 |
- HATs acetylate histones
- Formation of WDR5-containing histone-modifying complexes
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LAYN |
layilin |
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MCTS1 |
MCTS1 re-initiation and release factor |
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MEN1 |
menin 1 |
- Formation of the beta-catenin:TCF transactivating complex
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Deactivation of the beta-catenin transactivating complex
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- RHO GTPases activate IQGAPs
- Post-translational protein phosphorylation
- Formation of WDR5-containing histone-modifying complexes
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- Primary hyperparathyroidism; Familial hyperparathyroidism (HRPT)
- Adrenal carcinoma
- Malignant islet cell carcinoma
- Carcinoid
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MTM1 |
myotubularin 1 |
- Synthesis of PIPs at the plasma membrane
- Synthesis of PIPs at the early endosome membrane
- Synthesis of PIPs at the late endosome membrane
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OXT |
oxytocin/neurophysin I prepropeptide |
- Vasopressin-like receptors
- G alpha (q) signalling events
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PAF1 |
PAF1 component of Paf1/RNA polymerase II complex |
- Formation of RNA Pol II elongation complex
- RNA Polymerase II Pre-transcription Events
- RNA Polymerase II Transcription Elongation
- E3 ubiquitin ligases ubiquitinate target proteins
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PAFAH1B2 |
platelet activating factor acetylhydrolase 1b catalytic subunit 2 |
- Neutrophil degranulation
- COPI-independent Golgi-to-ER retrograde traffic
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PLAAT4 |
phospholipase A and acyltransferase 4 |
- Acyl chain remodelling of PE
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PLPP2 |
phospholipid phosphatase 2 |
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PLXNB1 |
plexin B1 |
- G alpha (12/13) signalling events
- Sema4D mediated inhibition of cell attachment and migration
- Sema4D induced cell migration and growth-cone collapse
- RHOD GTPase cycle
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PPIE |
peptidylprolyl isomerase E |
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Neutrophil degranulation
- mRNA Splicing - Major Pathway
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PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
- Downregulation of TGF-beta receptor signaling
- Response of EIF2AK1 (HRI) to heme deficiency
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PSIP1 |
PC4 and SRSF1 interacting protein 1 |
- Integration of provirus
- 2-LTR circle formation
- Integration of viral DNA into host genomic DNA
- Autointegration results in viral DNA circles
- APOBEC3G mediated resistance to HIV-1 infection
- Vpr-mediated nuclear import of PICs
- Formation of WDR5-containing histone-modifying complexes
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