ZYX - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
ACTN1	actinin alpha 1	Platelet degranulation Syndecan interactions Nephrin family interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components RHOD GTPase cycle RHOBTB2 GTPase cycle RHOF GTPase cycle	Human calcitonin Copper
ATXN1	ataxin 1			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
BSPRY	B-box and SPRY domain containing
CASS4	Cas scaffold protein family member 4
CEBPA	CCAAT enhancer binding protein alpha	Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis		Acute myeloid leukemia (AML)
ENAH	ENAH actin regulator	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors
EVL	Enah/Vasp-like	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
HIPK3	homeodomain interacting protein kinase 3		Fostamatinib
IMP3	IMP U3 small nucleolar ribonucleoprotein 3	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
LAP3	leucine aminopeptidase 3		Leucine Phosphonic Acid (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid Zofenoprilat
LASP1	LIM and SH3 protein 1
LATS1	large tumor suppressor kinase 1	Signaling by Hippo	Fostamatinib
LIN7A	lin-7 cell polarity scaffold A	Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
NEBL	nebulette
NEDD9	neural precursor cell expressed, developmentally down-regulated 9
NME5	NME/NM23 family member 5
OPRM1	opioid receptor mu 1	Opioid Signalling G-protein activation Peptide ligand-binding receptors G alpha (i) signalling events Interleukin-4 and Interleukin-13 signaling MECP2 regulates neuronal receptors and channels	Tramadol Morphine Codeine Amitriptyline Hydromorphone Methadone Meperidine Oxycodone Levallorphan Dextromethorphan Butorphanol Dextropropoxyphene Pentazocine Naltrexone Sufentanil Alfentanil Fentanyl Loperamide Nalbuphine Levorphanol Remifentanil Ondansetron Anileridine Buprenorphine Hydrocodone Diphenoxylate Naloxone Oxymorphone Dezocine Ketamine Levacetylmethadol Aripiprazole Methadyl acetate 3-Methylthiofentanyl Dimethylthiambutene Diamorphine Ethylmorphine Etorphine Carfentanil Diprenorphine Dihydromorphine 3-Methylfentanyl V1003 Epicept NP-1 LI-301 Tapentadol Nalmefene Alvimopan Amisulpride Morphine glucuronide Ketobemidone Methylnaltrexone Naloxegol Cannabidiol Trimebutine Butyrfentanyl Pholcodine Eluxadoline Tianeptine Opium Pentoxyverine Naldemedine Samidorphan Metenkefalin Medical Cannabis Nabiximols Loxicodegol Oliceridine
PDLIM5	PDZ and LIM domain 5	Neurexins and neuroligins
PHF21A	PHD finger protein 21A	HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
QRICH1	glutamine rich 1

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