ZYX and IMP3

Number of citations of the paper that reports this interaction (PubMedID 29892012)
71

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		ZYX	IMP3
Description		zyxin	IMP U3 small nucleolar ribonucleoprotein 3
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Phagocytic Vesicle Anchoring Junction	Nucleus Nucleoplasm Nucleolus Cytosol Preribosome Small-subunit Processome Mpp10 Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	RNA Binding Protein Binding RRNA Binding SnoRNA Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Stress Fiber Assembly Cellular Response To Type II Interferon	RRNA Processing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		Artenimol
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		36 interacting genes: ACTN1 ATXN1 BSPRY CASS4 CEBPA ENAH EVL HIPK3 IMP3 LAP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A QRICH1 RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384 ZNF512B	15 interacting genes: CCNDBP1 EFHC1 EVI5 KLC3 LPXN MPHOSPH10 NANOS3 PPP1R12C SERTAD3 SORBS3 TFIP11 TNFRSF9 USHBP1 ZNF655 ZYX
Entrez ID		7791	55272
HPRD ID		03592	12664
Ensembl ID		ENSG00000159840	ENSG00000177971
Uniprot IDs		Q15942 Q96AF9	Q9NV31
PDB IDs			2CQJ 7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Focal Adhesion Profilin Binding Anchoring Junction Actin Filament Organization Actin Binding Postsynapse Regulation Of Cellular Component Size Cytoplasm Stress Fiber Supramolecular Fiber Organization Lymphocyte Migration Into Lymphoid Organs Positive Regulation Of Protein Tyrosine Kinase Activity Actin Polymerization Or Depolymerization Platelet Activation Cytoskeletal Protein Binding Cytoskeleton Lamellipodium Regulation Of Cell Size
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