HSBP1 and SDR42E1

		HSBP1	SDR42E1
Description		heat shock factor binding protein 1	short chain dehydrogenase/reductase family 42E, member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Axon Cytoplasm	Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding	Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Axonal Transport Of Mitochondrion Endodermal Cell Differentiation Cellular Heat Acclimation	Steroid Biosynthetic Process
Pathways		HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		20 interacting genes: BLOC1S5 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 UBC WASHC1 WASHC3 ZBTB25	1 interacting genes: SRPK2
Entrez ID		3281	93517
HPRD ID		05185	17118
Ensembl ID		ENSG00000230989	ENSG00000184860
Uniprot IDs		O75506	Q8WUS8
PDB IDs		3CI9
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Negative Regulation Of Inclusion Body Assembly Response To Unfolded Protein WASH Complex Cellular Response To Unfolded Protein Regulation Of Inclusion Body Assembly	Cellular Heat Acclimation Nuclear Speck Organization R-loop Processing
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