HSBP1

Description		heat shock factor binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Axon Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Axonal Transport Of Mitochondrion Endodermal Cell Differentiation Cellular Heat Acclimation
Pathways		HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Novel Interacting Genes		24 novel interacting genes: BLOC1S5 CD1B CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPHOSPH6 MPP7 NOTCH2NLA RPL13 SDCBP SDCBP2 SDR42E1 UBC WASHC1 WASHC3 ZBTB25
Interacting Genes		24 interacting genes: BLOC1S5 CD1B CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPHOSPH6 MPP7 NOTCH2NLA RPL13 SDCBP SDCBP2 SDR42E1 UBC WASHC1 WASHC3 ZBTB25
Entrez ID		3281
HPRD ID		05185
Ensembl ID		ENSG00000230989
Uniprot IDs		O75506
PDB IDs		3CI9
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Negative Regulation Of Inclusion Body Assembly Response To Unfolded Protein WASH Complex Cellular Response To Unfolded Protein Regulation Of Inclusion Body Assembly
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