PLCH2 and CEP104

		PLCH2	CEP104
Description		phospholipase C eta 2	centrosomal protein 104
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Spindle Pole Cytoplasm Centrosome Centriole Cytoskeleton Cilium Cell Projection
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Phospholipase C Activity Calcium Ion Binding Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Lipid Catabolic Process Intracellular Signal Transduction Phosphatidylinositol Metabolic Process Phosphatidylinositol-mediated Signaling Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Body mass index ( 26426971) Irritable mood ( 29500382) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Ulcerative colitis ( 21297633 23128233)	Glycated hemoglobin levels ( 31213470) Mean corpuscular volume ( 27863252)
Interacting Genes		3 interacting genes: AGTR1 HRAS TNKS
Entrez ID		9651	9731
HPRD ID		18986	11091
Ensembl ID		ENSG00000149527	ENSG00000116198
Uniprot IDs		O75038	O60308
PDB IDs			5LPH 5LPI
Enriched GO Terms of Interacting Partners?			Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Phospholipase C Activity Phosphatidylinositol-mediated Signaling Negative Regulation Of Sequestering Of Calcium Ion Phosphoric Diester Hydrolase Activity Release Of Sequestered Calcium Ion Into Cytosol Calcium Ion Transmembrane Import Into Cytosol Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Phosphatidylinositol Metabolic Process Regulation Of Sequestering Of Calcium Ion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?