PLCH2 and CAMTA1

		PLCH2	CAMTA1
Description		phospholipase C eta 2	calmodulin binding transcription activator 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Nucleus Cytoplasm
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Phospholipase C Activity Calcium Ion Binding Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding	DNA Binding Double-stranded DNA Binding Transcription Coregulator Activity Sequence-specific DNA Binding
	Biological Process	Lipid Metabolic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Lipid Catabolic Process Intracellular Signal Transduction Phosphatidylinositol Metabolic Process Phosphatidylinositol-mediated Signaling Release Of Sequestered Calcium Ion Into Cytosol	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Neuromuscular Process Controlling Balance Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Body mass index ( 26426971) Irritable mood ( 29500382) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Ulcerative colitis ( 21297633 23128233)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Alcohol dependence ( 26365420) Appendicular lean mass ( 33097823) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Body size at age 10 ( 32376654) Crohn's disease ( 28067908) DHEAS levels ( 34748635) Diastolic blood pressure ( 30224653) Feeling worry ( 29500382) Inflammatory bowel disease ( 28067908) Intralaminar thalamic nuclei volume ( 34006833) Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) ( 32355309) Mean platelet volume ( 32888494 27863252) Morning person ( 30696823) Neurociticism ( 29500382) Periodontal microbiota ( 22699663) Photic sneeze reflex ( 27182965) Platelet count ( 32888494) Platelet distribution width ( 27863252 32888494) Post bronchodilator FEV1 ( 26634245) Puberty onset ( 24770850) Puberty onset (breast development) ( 24770850) Rosacea symptom severity ( 29771307) Sleep duration (long sleep) ( 30846698) Stearic acid (18:0) levels ( 23362303) Survival in sporadic amyotrophic lateral sclerosis ( 27244217) Tourette's syndrome or obsessive-compulsive disorder ( 25158072) Ulcerative colitis ( 28067908)
Interacting Genes		3 interacting genes: AGTR1 HRAS TNKS	1 interacting genes: PEX14
Entrez ID		9651	23261
HPRD ID		18986	16681
Ensembl ID		ENSG00000149527	ENSG00000171735
Uniprot IDs		O75038	A0A0C4DGL0 A0A8V8TPQ2 A0A8V8TQ65 A0A8V8TQ84 A0A8V8TQ87 A0A8V8TQX9 G3V297 Q9Y6Y1
PDB IDs			2CXK
Enriched GO Terms of Interacting Partners?			Protein Import Into Peroxisome Matrix, Translocation Peroxisome Transport Along Microtubule Protein Import Into Peroxisome Matrix, Docking Peroxisomal Importomer Complex Protein Import Into Peroxisome Matrix, Substrate Release Protein Transmembrane Transporter Activity Protein Unfolding Protein Import Into Peroxisome Matrix, Receptor Recycling Receptor Recycling Peroxisomal Membrane Transport Microtubule Anchoring Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Peroxisome Organization Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Phospholipase C Activity Phosphatidylinositol-mediated Signaling Negative Regulation Of Protein Binding Intracellular Protein Transmembrane Transport Transmembrane Transport Beta-tubulin Binding Regulation Of Protein Binding Receptor Metabolic Process Phosphoric Diester Hydrolase Activity Protein Monoubiquitination Negative Regulation Of Sequestering Of Calcium Ion Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of DNA-binding Transcription Factor Activity Peroxisomal Membrane Protein Transmembrane Transport Organelle Transport Along Microtubule Calcium Ion Transmembrane Import Into Cytosol
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