GCC2 and SULT1C3

		GCC2	SULT1C3
Description		GRIP and coiled-coil domain containing 2	sulfotransferase family 1C member 3
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane	Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding	Alcohol Sulfotransferase Activity Aryl Sulfotransferase Activity Protein Binding Sulfotransferase Activity Transferase Activity Bile-salt Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding
	Biological Process	Protein Targeting To Lysosome Protein Transport Microtubule Organizing Center Organization Protein Localization To Golgi Apparatus Microtubule Anchoring Late Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Regulation Of Protein Exit From Endoplasmic Reticulum Recycling Endosome To Golgi Transport Golgi Ribbon Formation	Lipid Metabolic Process Sulfur Compound Metabolic Process Xenobiotic Metabolic Process Cholesterol Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		Retrograde transport at the Trans-Golgi-Network Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 27863252) Platelet distribution width ( 32888494)	Aluminium levels ( 26025379) Blood pressure ( 24954895) Diastolic blood pressure ( 27618448) Eyebrow thickness ( 26926045) Systolic blood pressure ( 27618448)
Interacting Genes		3 interacting genes: ARL1 SPOP SRPK2	1 interacting genes: SULT2B1
Entrez ID		9648	442038
HPRD ID		11001	18131
Ensembl ID		ENSG00000135968	ENSG00000196228
Uniprot IDs		A0A8I5QJB7 B3KR21 Q8IWJ2	Q6IMI6
PDB IDs		3BBP	2H8K 2REO
Enriched GO Terms of Interacting Partners?			Alcohol Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Sulfotransferase Activity Steroid Hormone Binding Recycling Endosome To Golgi Transport Late Endosome To Golgi Transport 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Golgi Ribbon Formation Sulfation Small Molecule Binding Microtubule Anchoring Regulation Of Protein Exit From Endoplasmic Reticulum Positive Regulation Of Epidermal Cell Differentiation Protein Localization To Golgi Apparatus Protein Targeting To Lysosome Positive Regulation Of Epidermis Development Golgi To Plasma Membrane Protein Transport Sulfotransferase Activity Cholesterol Binding Protein Targeting To Vacuole Regulation Of Epidermis Development Positive Regulation Of Epithelial Cell Differentiation Regulation Of Epidermal Cell Differentiation Protein Localization To Lysosome Establishment Of Protein Localization To Vacuole Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Microtubule Organizing Center Organization Protein Localization To Vacuole Retrograde Transport, Endosome To Golgi Post-Golgi Vesicle-mediated Transport Cholesterol Metabolic Process Sterol Metabolic Process Lysosomal Transport Golgi Organization
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