MARS2 and COQ10B

		MARS2	COQ10B
Description		methionyl-tRNA synthetase 2, mitochondrial	coenzyme Q10B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Nucleotide Binding Aminoacyl-tRNA Ligase Activity Methionine-tRNA Ligase Activity ATP Binding Ligase Activity	Ubiquinone Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Methionyl-tRNA Aminoacylation	Cellular Respiration
Pathways		Mitochondrial tRNA aminoacylation	Respiratory electron transport Complex IV assembly
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Idiopathic dilated cardiomyopathy ( 29495422) Morning person ( 30696823) Schizophrenia ( 25056061 29483656) Stroke ( 32693751) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Morning person ( 30696823) Schizophrenia ( 25056061 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: APP OGT
Entrez ID		92935	80219
HPRD ID		14363	08582
Ensembl ID		ENSG00000247626	ENSG00000115520
Uniprot IDs		Q96GW9	B8ZZV9 B8ZZX2 Q9H8M1
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly TRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase Activity Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Synapse Assembly Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Endosome To Plasma Membrane Transport Vesicle Hemopoiesis Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Cell Development Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Ubiquinone Binding Wybutosine Biosynthetic Process Membrane Curvature Sensor Activity Membrane Bending Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway	Deacylase Activity Phosphatidylinositol Deacylase Activity DsRNA Transport Methionyl-tRNA Aminoacylation Methionine-tRNA Ligase Activity Positive Regulation Of ER To Golgi Vesicle-mediated Transport Forebrain Regionalization Attachment Of GPI Anchor To Protein Regulation Of ER To Golgi Vesicle-mediated Transport
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