RCCD1 and CRTC3

		RCCD1	CRTC3
Description		RCC1 domain containing 1	CREB regulated transcription coactivator 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome Cytosol Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding CAMP Response Element Binding Protein Binding
	Biological Process	Chromatin Organization	Lipid Catabolic Process Macrophage Activation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Cellular Response To CAMP Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Energy Homeostasis
Pathways		Protein hydroxylation	Transcriptional activation of mitochondrial biogenesis Heme signaling Expression of BMAL (ARNTL), CLOCK, and NPAS2
Drugs
Diseases
GWAS		Height ( 33713608) Red cell distribution width ( 28957414) Sleep duration ( 30531941)	Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 23128233 28067908) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)
Interacting Genes			5 interacting genes: CA13 KLHL12 SIK2 YAP1 YWHAG
Entrez ID		91433	64784
HPRD ID		18706	13384
Ensembl ID		ENSG00000166965	ENSG00000140577
Uniprot IDs		A6NED2	Q6UUV7
PDB IDs		6F4R 6F4S 6F4T
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway CAMP Response Element Binding Protein Binding Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Regulation Of Lipid Catabolic Process Macrophage Activation Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To CAMP Energy Homeostasis Response To CAMP Protein Tetramerization Negative Regulation Of Lipid Metabolic Process Myeloid Leukocyte Activation Response To Purine-containing Compound Regulation Of G Protein-coupled Receptor Signaling Pathway
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