ZNF439 and TIMM29

		ZNF439	TIMM29
Description		zinc finger protein 439	translocase of inner mitochondrial membrane 29
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Protein Transporter Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Protein Transport Protein Insertion Into Mitochondrial Inner Membrane
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131)
Interacting Genes		24 interacting genes: CARD10 CCNDBP1 CEP70 CLIC6 CYSRT1 GMNN KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-12 KRTAP5-9 KRTAP9-3 LMNA MDFI MTUS2 NOTCH2NLA PLEKHF2 TRIM41	2 interacting genes: APOE MAILR
Entrez ID		90594	90580
HPRD ID		11717	14275
Ensembl ID		ENSG00000171291	ENSG00000142444
Uniprot IDs		A0A0C4DG37 A0A804HI69 Q8NDP4	Q9BSF4
PDB IDs			7CGP
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Phospholipid Efflux Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of RNA Biosynthetic Process Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Presynaptic Membrane Organization Regulation Of Nucleobase-containing Compound Metabolic Process Chylomicron Remnant Lipid Transport Involved In Lipid Storage Lipoprotein Particle Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle Zinc Ion Binding DNA Binding Intermediate-density Lipoprotein Particle Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipoprotein Transport Negative Regulation Of Dendritic Spine Maintenance Very-low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Very-low-density Lipoprotein Particle Clearance Multivesicular Body, Internal Vesicle Positive Regulation Of Phospholipid Efflux Positive Regulation Of Amyloid Fibril Formation AMPA Glutamate Receptor Clustering NMDA Glutamate Receptor Clustering Positive Regulation Of Inclusion Body Assembly Triglyceride-rich Lipoprotein Particle Clearance Positive Regulation Of Dendritic Spine Maintenance Regulation Of Plasma Lipoprotein Particle Levels Chylomicron Remnant Clearance Protein-phosphatidylethanolamide Deconjugating Activity Cysteine-type Exopeptidase Activity Protein Delipidation Regulation Of Peroxisome Size Regulation Of Neurofibrillary Tangle Assembly Lipoprotein Biosynthetic Process Phosphatidylcholine-sterol O-acyltransferase Activator Activity Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process
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