RRP1 and PSMG1

		RRP1	PSMG1
Description		ribosomal RNA processing 1	proteasome assembly chaperone 1
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GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Preribosome, Small Subunit Precursor	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Protein Folding Chaperone Complex
	Molecular Function	RNA Binding Protein Binding	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	RRNA Processing	Cerebellar Granule Cell Precursor Proliferation Proteasome Assembly Chaperone-mediated Protein Complex Assembly Proteasome Core Complex Assembly
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Proteasome assembly Proteasome assembly
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Ankylosing spondylitis ( 20062062) C-reactive protein levels ( 21300955) Daytime nap ( 33568662) Daytime sleep phenotypes ( 27126917) Eye morphology ( 29921221) Fibrinogen ( 23969696) Fibrinogen levels ( 26561523 28107422) Finger osteoarthritis severity (hand Klsum) ( 33055079) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340) Inflammatory bowel disease ( 18758464) Pediatric autoimmune diseases ( 26301688) Primary sclerosing cholangitis ( 27992413 23603763) Serum alkaline phosphatase levels ( 33547301) Takayasu arteritis ( 23830517) Triglyceride levels ( 32203549) Ulcerative colitis ( 20228799)
Interacting Genes		4 interacting genes: MDM2 OGT SPANXN2 SRPK2	10 interacting genes: BRCA1 CEBPA CSDE1 PRKAR1A PRKAR1B PSMG2 SNRNP70 SPTAN1 UBE2A YME1L1
Entrez ID		8568	8624
HPRD ID		10857	05598
Ensembl ID		ENSG00000160214	ENSG00000183527
Uniprot IDs		P56182	O95456
PDB IDs		8FKP 8FKR 8FKT 8FKV	8QYJ 8QYL 8QYM 8QYN 8QYS 8QZ9 8TM3 8TM4 8TM5 8TM6 8YIX 8YIY 8YIZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Protein Modification Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Vitamin B1 NEDD8 Ligase Activity Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Nutrient Transferase Activity Protein-containing Complex Organization Response To Actinomycin D Receptor Serine/threonine Kinase Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Response To Water-immersion Restraint Stress Response To Formaldehyde Cellular Response To Vitamin B1 Negative Regulation Of Proteolysis Traversing Start Control Point Of Mitotic Cell Cycle Cellular Response To UV-C Protein-containing Complex Assembly Cellular Response To Actinomycin D Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Response To Nutrient Nuclear Speck Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein Glycosylation Glycoprotein Biosynthetic Process Glycosylation Macromolecule Glycosylation Protein O-linked Glycosylation Positive Regulation Of Transcription By Glucose Glycosyltransferase Activity Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Proteasome Core Complex Assembly Carbon Catabolite Regulation Of Transcription Atrial Septum Development Fibroblast Activation Peroxisome Proliferator Activated Receptor Binding Cellular Response To Antibiotic Cellular Response To Nutrient Levels 5S RRNA Binding R-loop Processing Glycoprotein Metabolic Process Regulation Of Transcription By Glucose Cell Proliferation In External Granule Layer Cerebellar Granule Cell Precursor Proliferation N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity	CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Cellular Response To Tumor Necrosis Factor Protein Kinase A Catalytic Subunit Binding Response To Tumor Necrosis Factor CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Postreplication Repair Cellular Response To Cytokine Stimulus Ubiquitin Conjugating Enzyme Activity Regulation Of CAMP/PKA Signal Transduction Multivesicular Body Ciliary Base RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Iduronate-2-sulfatase Activity
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