PIGO and MAP7

		PIGO	MAP7
Description		phosphatidylinositol glycan anchor biosynthesis class O	microtubule associated protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Plasma Membrane Microtubule Cytoskeleton Membrane Basolateral Plasma Membrane Axon Perinuclear Region Of Cytoplasm
	Molecular Function	Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Phosphotransferase Activity, For Other Substituted Phosphate Groups Mannose-ethanolamine Phosphotransferase Activity	Signaling Receptor Binding Structural Molecule Activity Protein Binding
	Biological Process	GPI Anchor Biosynthetic Process	Microtubule Cytoskeleton Organization Response To Osmotic Stress Establishment Or Maintenance Of Cell Polarity Protein Localization To Plasma Membrane
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Response to quetiapine in schizophrenia ( 29503163) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)	Cerebrospinal fluid sTREM-2 levels ( 31708768) Lung cancer ( 34062886) Pursuit maintenance gain ( 29064472)
Interacting Genes		2 interacting genes: APP PIGF	9 interacting genes: CCDC70 CLIP4 CLK1 POT1 SRPK2 TERF1 TRPV4 UBC ZNF114
Entrez ID		84720	9053
HPRD ID		15134	04982
Ensembl ID		ENSG00000165282	ENSG00000135525
Uniprot IDs		Q8TEQ8	A0A087WZ40 B7Z3E1 B7Z3Y3 B7ZB64 Q14244
PDB IDs			7SGS
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Perinuclear Region Of Cytoplasm Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Positive Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Low-density Lipoprotein Particle Mediated Signaling Collagen Type XV Trimer Phosphorylase Kinase Complex Phosphorylase Kinase Activity Positive Regulation Of Glycogen Catabolic Process Ethanolaminephosphotransferase Activity Microtubule-based Process Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Glycogen Catabolic Process Peptidase Activator Activity Cellular Response To Manganese Ion Antifungal Humoral Response Nuclear Envelope Lumen	Shelterin Complex Nuclear Telomere Cap Complex Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Osmosensor Activity Blood Vessel Endothelial Cell Delamination Stretch-activated, Monoatomic Cation-selective, Calcium Channel Activity Cytoplasmic Microtubule Organization Positive Regulation Of Telomere Maintenance DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of DNA Biosynthetic Process Positive Regulation Of Telomeric Loop Disassembly Positive Regulation Of Macrophage Inflammatory Protein 1 Alpha Production Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Cellular Hypotonic Salinity Response Vasopressin Secretion Mannose-ethanolamine Phosphotransferase Activity Nuclear Speck Organization Telomeric D-loop Binding Telomere Assembly Telomere Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Single-stranded Telomeric DNA Binding
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