ZNF594 and PITPNM3

		ZNF594	PITPNM3
Description		zinc finger protein 594	PITPNM family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm Cytosol Endomembrane System Membrane Cell Projection Cell Body
	Molecular Function	DNA Binding Zinc Ion Binding Metal Ion Binding	Phospholipase Activity Calcium Ion Binding Protein Binding Phospholipid Transporter Activity Lipid Binding Phosphatidylinositol Transfer Activity Receptor Tyrosine Kinase Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Phosphatidylinositol Biosynthetic Process Phospholipid Transport Intermembrane Lipid Transfer
Pathways			Synthesis of PI
Drugs
Diseases			Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS			Diastolic blood pressure ( 30578418) FEV1 ( 30804560) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 27841878) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878)
Interacting Genes		1 interacting genes: GOLGA2	1 interacting genes: PTK2B
Entrez ID		84622	83394
HPRD ID		15867	07498
Ensembl ID		ENSG00000180626	ENSG00000091622
Uniprot IDs		Q6ZNC6 Q96JF6	A1A5C9 Q9BZ71
PDB IDs
Enriched GO Terms of Interacting Partners?			Neurotransmitter Receptor Regulator Activity Positive Regulation Of B Cell Chemotaxis NMDA Selective Glutamate Receptor Complex Signal Complex Assembly Peptidyl-tyrosine Autophosphorylation Marginal Zone B Cell Differentiation Signaling Receptor Activator Activity Activation Of Janus Kinase Activity Bone Resorption Apical Dendrite Negative Regulation Of Potassium Ion Transport Calcium/calmodulin-dependent Protein Kinase Activity Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Macrophage Chemotaxis Mature B Cell Differentiation Positive Regulation Of Excitatory Postsynaptic Potential Cellular Response To Fluid Shear Stress Regulation Of Postsynaptic Density Assembly Postsynaptic Density, Intracellular Component Endothelin Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Lymphocyte Chemotaxis Mature B Cell Differentiation Involved In Immune Response Positive Regulation Of Lymphocyte Chemotaxis Regulation Of Postsynaptic Specialization Assembly Negative Regulation Of Biomineral Tissue Development Ionotropic Glutamate Receptor Binding Negative Regulation Of Bone Mineralization Regulation Of Excitatory Synapse Assembly Glutamate Receptor Signaling Pathway Regulation Of Macrophage Migration Cellular Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Cortical Cytoskeleton Organization Activation Of Protein Kinase Activity Negative Regulation Of Ossification Positive Regulation Of Actin Filament Polymerization Sprouting Angiogenesis Positive Regulation Of Lymphocyte Migration Response To Fluid Shear Stress Ligand-gated Ion Channel Signaling Pathway Modulation Of Excitatory Postsynaptic Potential Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Long-term Synaptic Potentiation Positive Regulation Of Cell-matrix Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway
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