QRFPR and BBS12

		QRFPR	BBS12
Description		pyroglutamylated RFamide peptide receptor	Bardet-Biedl syndrome 12
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cilium Cell Projection
	Molecular Function	G Protein-coupled Receptor Activity Neuropeptide Y Receptor Activity Protein Binding	Protein Binding ATP Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cellular Response To Hormone Stimulus	Intraciliary Transport Eating Behavior Fat Cell Differentiation Photoreceptor Cell Maintenance Negative Regulation Of Fat Cell Differentiation Stem Cell Differentiation Chaperone-mediated Protein Complex Assembly Negative Regulation Of Stem Cell Differentiation
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Weight ( 34074324)	Asthma ( 31959851) Caudate nucleus volume ( 31530798) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Metabolite levels ( 23823483) Mosquito bite size ( 28199695) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: GJA8 NTM
Entrez ID		84109	166379
HPRD ID		09494	08759
Ensembl ID		ENSG00000186867	ENSG00000181004
Uniprot IDs		F2Z3L3 Q96P65	Q6ZW61
PDB IDs		8WZ2 8ZH8
Enriched GO Terms of Interacting Partners?		Eye Development Fat Cell Differentiation Pigment Granule Aggregation In Cell Center Primary Palate Development Sensory Organ Development Gap Junction-mediated Intercellular Transport BBSome Intercellular Transport
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