TSSK6 and MPV17L2

		TSSK6	MPV17L2
Description		testis specific serine kinase 6	MPV17 mitochondrial inner membrane protein like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal Microtubule Doublet Inner Sheath	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding Protein Serine Kinase Activity	Mitochondrial Large Ribosomal Subunit Binding
	Biological Process	Protein Phosphorylation Spermatogenesis Spermatid Development Cell Differentiation Flagellated Sperm Motility Sperm DNA Condensation	Mitochondrial Ribosome Assembly Positive Regulation Of Mitochondrial Translation
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Percent liver fat ( 34128465) Refractive error ( 32231278) Schizophrenia ( 23974872 25056061 29483656)	A body shape index ( 34021172) Multiple sclerosis ( 21833088) Serum alkaline phosphatase levels ( 33547301) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		8 interacting genes: APP H2AC20 H2AX H3C1 HSP90AB1 HSPA1A HSPA8 MBP
Entrez ID		83983	84769
HPRD ID		15441	13324
Ensembl ID		ENSG00000178093	ENSG00000254858
Uniprot IDs		A0A024R7Q5 Q9BXA6	Q567V2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Import Extracellular Exosome ATP-dependent Protein Folding Chaperone C3HC4-type RING Finger Domain Binding ATP-dependent Protein Disaggregase Activity Protein Folding Chaperone Heat Shock Protein Binding G Protein-coupled Receptor Binding Protein-containing Complex Organization Structural Constituent Of Chromatin Response To Unfolded Protein Epigenetic Regulation Of Gene Expression Cadherin Binding Unfolded Protein Binding Cellular Component Assembly Protein Heterodimerization Activity Nucleosome Ficolin-1-rich Granule Lumen Receptor Ligand Activity Chaperone-mediated Protein Complex Assembly Regulation Of Macromolecule Metabolic Process Enzyme Binding Regulation Of Proteolysis Protein-containing Complex Protein-containing Complex Assembly Disordered Domain Specific Binding MHC Class II Protein Complex Binding Protein Refolding Protein Folding Chaperone Complex COP9 Signalosome Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Proteolysis Positive Regulation Of Nitric Oxide Metabolic Process Protein Folding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleus Cellular Response To Heat Chaperone-mediated Autophagy Translocation Complex Disassembly Positive Regulation Of Metalloendopeptidase Activity Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Chromatin Remodeling Acetylcholine Receptor Activator Activity Positive Regulation Of Metabolic Process	Axonemal Microtubule Doublet Inner Sheath Sperm DNA Condensation Sperm Flagellum Sperm Motility Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Cilium-dependent Cell Motility Spermatid Development
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