CDCA7 and MYO18A

		CDCA7	MYO18A
Description		cell division cycle associated 7	myosin XVIIIA
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Cytoskeleton Cell Surface Actin Cytoskeleton Membrane Myosin Complex Myosin II Complex Myosin Filament Actomyosin
	Molecular Function	Protein Binding Hemi-methylated DNA-binding	Nucleotide Binding DNA Binding RNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA ATP Hydrolysis Activity ADP Binding Actin Filament Binding
	Biological Process	Regulation Of DNA-templated Transcription Apoptotic Process Regulation Of Cell Population Proliferation	DNA Metabolic Process Apoptotic Process Golgi Organization Canonical NF-kappaB Signal Transduction Cell Migration Actomyosin Structure Organization Regulation Of Macrophage Activation Negative Regulation Of Apoptotic Process Golgi Vesicle Budding Positive Regulation Of Protein Secretion Golgi Ribbon Formation Asymmetric Golgi Ribbon Formation Positive Regulation Of Opsonization
Pathways			Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins
Drugs
Diseases
GWAS		Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Asthma ( 27611488) Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Blood pressure measurement (low sodium intervention) ( 24165912) Breast cancer ( 23535729 29059683) End-stage renal disease in Type 1 diabetics ( 24029427) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Male-pattern baldness ( 27182965 29146897) Mosquito bite size ( 28199695) Otitis media (chronic/recurrent) ( 23974705) Prostate cancer ( 29892016) Sensation seeking ( 30718321)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Hemoglobin levels ( 33491795) Hip circumference adjusted for BMI ( 34021172) Night sleep phenotypes ( 27126917) Sitting height ratio ( 25865494) Smoking behaviour (cigarette pack-years) ( 30679032) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		1 interacting genes: APP	5 interacting genes: ARAF ATXN1 GRB2 LINC01554 RNF10
Entrez ID		83879	399687
HPRD ID		09874	10106
Ensembl ID		ENSG00000144354	ENSG00000196535
Uniprot IDs		Q9BWT1	A0A994J771 Q92614 Q9NYE8
PDB IDs		8TLK 8YV8
Enriched GO Terms of Interacting Partners?		Golgi Ribbon Formation Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Protein Homooligomerization Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Microtubule-based Transport Transport Along Microtubule Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Microtubule-based Process Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Protein Glycosylation Golgi Organization Asymmetric Golgi Ribbon Formation Golgi Vesicle Budding Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Protein Complex Oligomerization Intracellular Transport NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Protein Transport Golgi Disassembly Axon Choice Point Recognition Regulation Of Protein Glycosylation
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