RPS6KL1 and MIDEAS

		RPS6KL1	MIDEAS
Description		ribosomal protein S6 kinase like 1	mitotic deacetylase associated SANT domain protein
Image		No pdb structure
GO Annotations	Cellular Component	Ribosome Ribonucleoprotein Complex	Histone Deacetylase Complex Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	DNA Binding Transcription Corepressor Activity Protein Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) HDL cholesterol levels ( 32203549) Mood instability ( 29187730) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes			1 interacting genes: MAPK14
Entrez ID		83694	91748
HPRD ID		18004	12648
Ensembl ID		ENSG00000198208	ENSG00000156030
Uniprot IDs		B4DSP6 Q9Y6S9	A0A1C7CYX1 Q6PJG2
PDB IDs			6Z2J 6Z2K
Enriched GO Terms of Interacting Partners?		DRM Complex	Cell Aggregation Positive Regulation Of Myotube Differentiation Positive Regulation Of Heart Growth Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Hippo Signaling 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Proliferation Regulation Of Brown Fat Cell Differentiation Cellular Response To Lipoteichoic Acid P38MAPK Cascade Hexose Transmembrane Transport Regulation Of Hippo Signaling Protein Serine Kinase Activity Cellular Response To UV-B Response To UV-B Regulation Of Myotube Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway D-glucose Import Positive Regulation Of D-glucose Import Cellular Response To Vascular Endothelial Growth Factor Stimulus D-glucose Transmembrane Transport Carbohydrate Transmembrane Transport Positive Regulation Of D-glucose Transmembrane Transport MAP Kinase Activity Osteoclast Differentiation Positive Regulation Of Myoblast Fusion Positive Regulation Of Organ Growth Cartilage Condensation Mitogen-activated Protein Kinase P38 Binding Pyroptotic Inflammatory Response MAP Kinase Kinase Activity Positive Regulation Of Cyclase Activity Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Striated Muscle Cell Differentiation Stress-activated MAPK Cascade Placenta Development Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Synaptic Membrane Adhesion Regulation Of Myoblast Fusion Positive Regulation Of Protein Import Into Nucleus Carbohydrate Transport Kinase Activity Positive Regulation Of Interleukin-12 Production NFAT Protein Binding Stress-induced Premature Senescence Protein Kinase Activity Canonical Inflammasome Complex Assembly
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