DRC3 and SPECC1

		DRC3	SPECC1
Description		dynein regulatory complex subunit 3	sperm antigen with calponin homology and coiled-coil domains 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Membrane Filamentous Actin Apical Part Of Cell
	Molecular Function	Protein Binding
	Biological Process		Blastocyst Development Associative Learning Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 30285260)
Interacting Genes		2 interacting genes: MFHAS1 ZNF250	2 interacting genes: FXR1 ITSN1
Entrez ID		83450	92521
HPRD ID		13181	12301
Ensembl ID		ENSG00000171962	ENSG00000128487
Uniprot IDs		B3KSC6 Q9H069	A0A7I2V416 A0A7I2YQJ3 A0A7P0TAS3 A0A7P0TBP2 B4DW07 B4E2A4 J3KRB9 J3KSG2 Q5M775
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?			Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Caveolin-mediated Endocytosis Dendritic Spine Clathrin-dependent Synaptic Vesicle Endocytosis Nuclear Envelope Neuron Projection Cell Projection Regulation Of Caveolin-mediated Endocytosis Regulation Of Modification Of Postsynaptic Actin Cytoskeleton RNA Strand Annealing Activity Nuclear Pore Localization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Intracellular Membraneless Organelle Postsynaptic Endocytic Zone Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Long-term Neuronal Synaptic Plasticity Postsynaptic Actin Cytoskeleton Nuclear Pore Complex Assembly Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of Growth Hormone Secretion Regulation Of Modification Of Postsynaptic Structure Costamere Ribonucleoprotein Granule Nuclear Pore Organization Apical Dendrite Intracellular Vesicle Proline-rich Region Binding Glutamatergic Synapse Regulation Of Modification Of Synaptic Structure Skeletal Muscle Organ Development Translation Regulator Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Pore Complex Assembly Regulation Of Circadian Sleep/wake Cycle MRNA 3'-UTR AU-rich Region Binding Dentate Gyrus Development Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Rho Protein Signal Transduction Clathrin-dependent Endocytosis Cytoplasmic Translational Initiation Positive Regulation Of Dendritic Spine Development Synaptic Vesicle Endocytosis Ribonucleoprotein Complex Binding Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Long-term Synaptic Potentiation Presynaptic Endocytosis Synapse
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