B9D2 and ZNF574

		B9D2	ZNF574
Description		B9 domain containing 2	zinc finger protein 574
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cilium Membrane MKS Complex Ciliary Basal Body Cell Projection	Nucleus
	Molecular Function	Protein Binding Gamma-tubulin Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Cell Projection Organization Cilium Assembly	Regulation Of Transcription By RNA Polymerase II Developmental Process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 29212778 32469254) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)	Meat-related diet ( 32066663)
Interacting Genes		8 interacting genes: ALKBH7 P4HA3 PLEKHA7 QARS1 SAXO4 SPAG8 TLX3 VPS25	9 interacting genes: APP CEP70 DCDC2B FBXO7 GOLGA6L9 LHX3 MEOX2 POU6F2 TRAF2
Entrez ID		80776	64763
HPRD ID		14613	15853
Ensembl ID		ENSG00000123810	ENSG00000105732
Uniprot IDs		Q9BPU9	A0A0C4DFM2 Q6ZN55 Q71MF7
PDB IDs
Enriched GO Terms of Interacting Partners?			Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway TORC2 Complex Disassembly Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Gamma-tubulin Binding Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Ubiquitin Ligase Complex Sphingolipid Binding TRAF2-GSTP1 Complex IRE1-TRAF2-ASK1 Complex TORC1 Complex Assembly CD40 Receptor Binding Tumor Necrosis Factor Receptor Superfamily Complex Medial Motor Column Neuron Differentiation Ventral Spinal Cord Interneuron Specification Prolactin Secreting Cell Differentiation Somatotropin Secreting Cell Differentiation Lewy Body Core Microtubule Organizing Center Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cell Projection Organization Growth Factor Receptor Binding Main Axon
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