COQ8B and C19orf33

		COQ8B	C19orf33
Description		coenzyme Q8B	chromosome 19 open reading frame 33
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Mitochondrial Membrane	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity ATP Binding Lipid Binding Kinase Activity Transferase Activity ATP Hydrolysis Activity	Double-stranded DNA Binding Single-stranded DNA Binding
	Biological Process	Protein Phosphorylation Ubiquinone Biosynthetic Process Cerebellar Purkinje Cell Layer Morphogenesis	Biological_process
Pathways		Ubiquinol biosynthesis
Drugs		Fostamatinib
Diseases
GWAS			Mean platelet volume ( 27863252)
Interacting Genes		1 interacting genes: OGT	1 interacting genes: APP
Entrez ID		79934	64073
HPRD ID		10632	12706
Ensembl ID		ENSG00000123815	ENSG00000167644
Uniprot IDs		Q96D53	Q9GZP8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Regulation Of Transcription By Glucose NSL Complex Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Sin3-type Complex Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Regulation Of Protein Localization To Synapse Regulation Of Receptor Localization To Synapse Mitophagy Protein Localization To Lysosome Circadian Regulation Of Gene Expression Positive Regulation Of Stem Cell Population Maintenance Cellular Response To Glucose Stimulus Regulation Of Stem Cell Population Maintenance Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Carbohydrate Catabolic Process Regulation Of Gluconeogenesis Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Positive Regulation Of TORC1 Signaling Cellular Response To Carbohydrate Stimulus Regulation Of Necroptotic Process Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Phosphatidylinositol-3,4,5-trisphosphate Binding Pyroptotic Inflammatory Response Cellular Response To Nutrient Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Autophagy Of Mitochondrion Positive Regulation Of Translational Initiation Regulation Of Rac Protein Signal Transduction Negative Regulation Of Protein Ubiquitination TORC1 Signaling Regulation Of Insulin Receptor Signaling Pathway Regulation Of Programmed Necrotic Cell Death Positive Regulation Of TOR Signaling Chromatin DNA Binding Intracellular Glucose Homeostasis TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Purine Nucleotide Metabolic Process	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cerebellar Purkinje Cell Layer Morphogenesis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance
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