NARS2 and KCTD14

		NARS2	KCTD14
Description		asparaginyl-tRNA synthetase 2, mitochondrial	potassium channel tetramerization domain containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Aminoacyl-tRNA Ligase Activity Asparagine-tRNA Ligase Activity ATP Binding Ligase Activity	Protein Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Asparaginyl-tRNA Aminoacylation	Protein Homooligomerization
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Asparagine
Diseases
GWAS		Alzheimer's disease (survival time) ( 25649651) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Estimated glomerular filtration rate ( 31451708) High light scatter reticulocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Tourette syndrome ( 30818990) Verbal declarative memory ( 25648963)	Disease progression in age-related macular degeneration ( 29346644) Tourette syndrome ( 30818990)
Interacting Genes			3 interacting genes: FBXO7 STK16 TCF4
Entrez ID		79731	65987
HPRD ID		08026	13764
Ensembl ID		ENSG00000137513	ENSG00000151364
Uniprot IDs		A0A8Q3SHL5 A0A8Q3SHT7 A0A8Q3WKF4 B3KPX5 H0YE96 Q96I59 Q9H5H1	Q9BQ13
PDB IDs
Enriched GO Terms of Interacting Partners?		Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity	Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Beta-catenin-TCF7L2 Complex Lewy Body Core Asparagine-tRNA Ligase Activity Asparaginyl-tRNA Aminoacylation TFIIB-class Transcription Factor Binding
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