GDPD3 and DCTPP1

		GDPD3	DCTPP1
Description		glycerophosphodiester phosphodiesterase domain containing 3	dCTP pyrophosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Phosphatidylcholine Lysophospholipase Activity Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding	Nucleotide Binding Magnesium Ion Binding Protein Binding Pyrophosphatase Activity Hydrolase Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Metal Ion Binding Nucleoside Triphosphate Diphosphatase Activity DCTP Diphosphatase Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidylcholine Catabolic Process Glycerophospholipid Catabolic Process N-acylethanolamine Metabolic Process	DCTP Catabolic Process Nucleoside Triphosphate Catabolic Process DNA Protection DTTP Catabolic Process
Pathways		Glycerophospholipid catabolism	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 29483656)	Urinary sodium excretion ( 31409800)
Interacting Genes			12 interacting genes: APP FMR1 FXR1 FXR2 LNX1 NIF3L1 NOA1 NTAQ1 PSMA1 SDCBP SPG21 USP7
Entrez ID		79153	79077
HPRD ID		08330	18310
Ensembl ID		ENSG00000102886	ENSG00000179958
Uniprot IDs		Q7L5L3	Q9H773
PDB IDs			7MU5
Enriched GO Terms of Interacting Partners?		DTTP Catabolic Process DCTP Diphosphatase Activity DCTP Catabolic Process Pyrimidine Deoxyribonucleotide Binding Nucleoside Triphosphate Diphosphatase Activity DNA Protection Nucleoside Triphosphate Catabolic Process Pyrophosphatase Activity Pyrimidine Deoxyribonucleotide Catabolic Process Pyrimidine-containing Compound Catabolic Process Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process Deoxyribonucleotide Metabolic Process Pyrimidine Nucleotide Metabolic Process Pyrimidine-containing Compound Metabolic Process Nucleotide Catabolic Process Nucleoside Phosphate Catabolic Process Organophosphate Catabolic Process Carbohydrate Derivative Catabolic Process Magnesium Ion Binding Nucleobase-containing Compound Catabolic Process Nucleotide Metabolic Process	Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Translation Regulator Activity Growth Cone Filopodium Postsynapse RNA Strand Annealing Activity Presynaptic Modulation Of Chemical Synaptic Transmission Intracellular Membraneless Organelle Protein Heterodimerization Activity Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Cytoplasmic Ribonucleoprotein Granule Presynapse Collateral Sprouting Cytoplasmic Stress Granule DNA Repair Positive Regulation Of Catabolic Process Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization MRNA Transport MRNA 3'-UTR Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Dentate Gyrus Development Neuron Maturation Regulation Of Nucleobase-containing Compound Metabolic Process Neuron Projection Frizzled Binding Dendritic Spine RNA Transport Positive Regulation Of Translation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Intracellular Transport Of Viral Material Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Adrenal Cortex Development Regulation Of Long-term Synaptic Potentiation Chromosome Regulation Of RNA Metabolic Process Regulation Of Translation Molecular Condensate Scaffold Activity
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