DCTPP1 and GDPD3

		DCTPP1	GDPD3
Description		dCTP pyrophosphatase 1	glycerophosphodiester phosphodiesterase domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Binding Pyrophosphatase Activity Hydrolase Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Metal Ion Binding Nucleoside Triphosphate Diphosphatase Activity DCTP Diphosphatase Activity	Phosphatidylcholine Lysophospholipase Activity Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	DCTP Catabolic Process Nucleoside Triphosphate Catabolic Process DNA Protection DTTP Catabolic Process	Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidylcholine Catabolic Process Glycerophospholipid Catabolic Process N-acylethanolamine Metabolic Process
Pathways		Interconversion of nucleotide di- and triphosphates	Glycerophospholipid catabolism
Drugs
Diseases
GWAS		Urinary sodium excretion ( 31409800)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 29483656)
Interacting Genes		12 interacting genes: APP FMR1 FXR1 FXR2 LNX1 NIF3L1 NOA1 NTAQ1 PSMA1 SDCBP SPG21 USP7
Entrez ID		79077	79153
HPRD ID		18310	08330
Ensembl ID		ENSG00000179958	ENSG00000102886
Uniprot IDs		Q9H773	Q7L5L3
PDB IDs		7MU5
Enriched GO Terms of Interacting Partners?		Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Translation Regulator Activity Growth Cone Filopodium Postsynapse RNA Strand Annealing Activity Presynaptic Modulation Of Chemical Synaptic Transmission Intracellular Membraneless Organelle Protein Heterodimerization Activity Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Cytoplasmic Ribonucleoprotein Granule Presynapse Collateral Sprouting Cytoplasmic Stress Granule DNA Repair Positive Regulation Of Catabolic Process Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization MRNA Transport MRNA 3'-UTR Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Dentate Gyrus Development Neuron Maturation Regulation Of Nucleobase-containing Compound Metabolic Process Neuron Projection Frizzled Binding Dendritic Spine RNA Transport Positive Regulation Of Translation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Intracellular Transport Of Viral Material Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Adrenal Cortex Development Regulation Of Long-term Synaptic Potentiation Chromosome Regulation Of RNA Metabolic Process Regulation Of Translation Molecular Condensate Scaffold Activity	DTTP Catabolic Process DCTP Diphosphatase Activity DCTP Catabolic Process Pyrimidine Deoxyribonucleotide Binding Nucleoside Triphosphate Diphosphatase Activity DNA Protection Nucleoside Triphosphate Catabolic Process Pyrophosphatase Activity Pyrimidine Deoxyribonucleotide Catabolic Process Pyrimidine-containing Compound Catabolic Process Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process Deoxyribonucleotide Metabolic Process Pyrimidine Nucleotide Metabolic Process Pyrimidine-containing Compound Metabolic Process Nucleotide Catabolic Process Nucleoside Phosphate Catabolic Process Organophosphate Catabolic Process Carbohydrate Derivative Catabolic Process Magnesium Ion Binding Nucleobase-containing Compound Catabolic Process Nucleotide Metabolic Process
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