CUEDC2 and DPCD

		CUEDC2	DPCD
Description		CUE domain containing 2	deleted in primary ciliary dyskinesia homolog (mouse)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Extracellular Region Nucleus
	Molecular Function	Protein Binding Ubiquitin Binding	Protein Binding
	Biological Process	Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Ventricular System Development Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Establishment Of Localization In Cell Left/right Pattern Formation
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder-related traits ( 25534755) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Mean corpuscular volume ( 32888494)
Interacting Genes		12 interacting genes: AGTR1 CHUK ESR1 EWSR1 IKBKB MAPK1 MAPK3 MYCBP2 PGR SOCS1 SOCS3 UBC	2 interacting genes: APP RUVBL2
Entrez ID		79004	25911
HPRD ID		13099	13247
Ensembl ID		ENSG00000107874	ENSG00000166171
Uniprot IDs		Q9H467	Q5JQQ4 Q9BVM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response Intracellular Signal Transduction Cytokine-mediated Signaling Pathway Cellular Response To Tumor Necrosis Factor Stress-activated Protein Kinase Signaling Cascade Stress-activated MAPK Cascade Response To Tumor Necrosis Factor IkappaB Kinase Activity Interleukin-34-mediated Signaling Pathway Regulation Of Golgi Inheritance Phosphotyrosine Residue Binding Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Regulation Of Inflammatory Response Cellular Response To Cytokine Stimulus IkappaB Kinase Complex Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Positive Regulation Of Defense Response Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Bergmann Glial Cell Differentiation CD40 Receptor Complex Transferrin Receptor Binding Estrogen Response Element Binding Response To Cytokine Response To Peptide Protein Ubiquitination Mammary Gland Epithelial Cell Proliferation MAP Kinase Activity Cytoplasmic Side Of Plasma Membrane Protein Modification Process Regulation Of Golgi Organization Pseudopodium Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Protein Modification By Small Protein Conjugation Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of Neuroinflammatory Response Animal Organ Formation Nuclear Steroid Receptor Activity Identical Protein Binding Face Development Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT ERBB2 Signaling Pathway Protein Serine/threonine Kinase Activity Interleukin-1-mediated Signaling Pathway Positive Regulation Of Macrophage Migration
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