ZNF747 and DCTPP1

		ZNF747	DCTPP1
Description		zinc finger protein 747	dCTP pyrophosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding Magnesium Ion Binding Protein Binding Pyrophosphatase Activity Hydrolase Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Metal Ion Binding Nucleoside Triphosphate Diphosphatase Activity DCTP Diphosphatase Activity
	Biological Process	Regulation Of DNA-templated Transcription	DCTP Catabolic Process Nucleoside Triphosphate Catabolic Process DNA Protection DTTP Catabolic Process
Pathways		Generic Transcription Pathway	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)	Urinary sodium excretion ( 31409800)
Interacting Genes		4 interacting genes: APP APPBP2 INCA1 RHOU	12 interacting genes: APP FMR1 FXR1 FXR2 LNX1 NIF3L1 NOA1 NTAQ1 PSMA1 SDCBP SPG21 USP7
Entrez ID		65988	79077
HPRD ID		14498	18310
Ensembl ID		ENSG00000169955	ENSG00000179958
Uniprot IDs		A0A8I5KWK6 B7ZAD9 Q9BV97	Q9H773
PDB IDs			7MU5
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway DTTP Catabolic Process DCTP Diphosphatase Activity DCTP Catabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Pyrimidine Deoxyribonucleotide Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Nucleoside Triphosphate Diphosphatase Activity DNA Protection Heparan Sulfate Binding Signaling Receptor Activator Activity Positive Regulation Of Focal Adhesion Disassembly Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Antifungal Humoral Response Nuclear Envelope Lumen Nucleoside Triphosphate Catabolic Process Pyrophosphatase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity	Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Translation Regulator Activity Growth Cone Filopodium Postsynapse RNA Strand Annealing Activity Presynaptic Modulation Of Chemical Synaptic Transmission Intracellular Membraneless Organelle Protein Heterodimerization Activity Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Cytoplasmic Ribonucleoprotein Granule Presynapse Collateral Sprouting Cytoplasmic Stress Granule DNA Repair Positive Regulation Of Catabolic Process Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization MRNA Transport MRNA 3'-UTR Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Dentate Gyrus Development Neuron Maturation Regulation Of Nucleobase-containing Compound Metabolic Process Neuron Projection Frizzled Binding Dendritic Spine RNA Transport Positive Regulation Of Translation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Intracellular Transport Of Viral Material Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Adrenal Cortex Development Regulation Of Long-term Synaptic Potentiation Chromosome Regulation Of RNA Metabolic Process Regulation Of Translation Molecular Condensate Scaffold Activity
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