CRTC3 and RCCD1

		CRTC3	RCCD1
Description		CREB regulated transcription coactivator 3	RCC1 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Chromosome Cytosol Plasma Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding CAMP Response Element Binding Protein Binding	Protein Binding
	Biological Process	Lipid Catabolic Process Macrophage Activation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Cellular Response To CAMP Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Energy Homeostasis	Chromatin Organization
Pathways		Transcriptional activation of mitochondrial biogenesis Heme signaling Expression of BMAL (ARNTL), CLOCK, and NPAS2	Protein hydroxylation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 23128233 28067908) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)	Height ( 33713608) Red cell distribution width ( 28957414) Sleep duration ( 30531941)
Interacting Genes		5 interacting genes: CA13 KLHL12 SIK2 YAP1 YWHAG
Entrez ID		64784	91433
HPRD ID		13384	18706
Ensembl ID		ENSG00000140577	ENSG00000166965
Uniprot IDs		Q6UUV7	A6NED2
PDB IDs			6F4R 6F4S 6F4T
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway CAMP Response Element Binding Protein Binding Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Regulation Of Lipid Catabolic Process Macrophage Activation Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To CAMP Energy Homeostasis Response To CAMP Protein Tetramerization Negative Regulation Of Lipid Metabolic Process Myeloid Leukocyte Activation Response To Purine-containing Compound Regulation Of G Protein-coupled Receptor Signaling Pathway
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