CLRN2 and TAPT1

		CLRN2	TAPT1
Description		clarin 2	transmembrane anterior posterior transformation 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Stereocilium Bundle Cell Projection Stereocilium Membrane	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Centrosome Cytosol Cytoskeleton Cilium Membrane Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding	Growth Hormone-releasing Hormone Receptor Activity
	Biological Process	Sensory Perception Of Sound Inner Ear Auditory Receptor Cell Differentiation Auditory Receptor Cell Stereocilium Organization Stereocilium Maintenance	Ossification G Protein-coupled Receptor Signaling Pathway Neural Crest Cell Development Cell Projection Organization Cell Differentiation Positive Regulation Of Cilium Assembly Embryonic Skeletal System Development Cartilage Development Positive Regulation Of Cartilage Development Positive Regulation Of Bone Development
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613) Metabolite levels ( 23823483)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Glomerular filtration rate in chronic kidney disease ( 26420894) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		12 interacting genes: ARL6IP6 CLDN5 CLEC2D FNDC9 KLRC1 LRRC25 NEMP1 SIT1 SSMEM1 STOM TEX29 VSIR	2 interacting genes: SMAD1 SMURF1
Entrez ID		645104	202018
HPRD ID		19335	08290
Ensembl ID		ENSG00000249581	ENSG00000169762
Uniprot IDs		A0PK11	B4DJJ3 Q6NXT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	I-SMAD Binding BMP Signaling Pathway Engulfment Of Target By Autophagosome Mesodermal Cell Fate Commitment Homomeric SMAD Protein Complex Osteoblast Fate Commitment Stereocilium Maintenance Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Anti-Mullerian Hormone Receptor Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Stereocilium Membrane Heteromeric SMAD Protein Complex SMAD Protein Complex DEAD/H-box RNA Helicase Binding Activin Receptor Binding Substrate Localization To Autophagosome
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