SDF2 and CCL15

		SDF2	CCL15
Description		stromal cell derived factor 2	C-C motif chemokine ligand 15
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Protein Folding Chaperone Complex	Extracellular Region Extracellular Space
	Molecular Function	Misfolded Protein Binding	Signaling Receptor Binding Cytokine Activity Chemokine Activity Heparin Binding Chemoattractant Activity CCR Chemokine Receptor Binding
	Biological Process	Protein Refolding	Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Migration Positive Regulation Of Inflammatory Response Positive Chemotaxis Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways
Drugs		Malonate Ion
Diseases
GWAS			Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Upper eyelid sagging severity ( 24869959)
Interacting Genes		3 interacting genes: HNRNPD HSPB2 UBC	3 interacting genes: CCL2 CCR1 CCR3
Entrez ID		6388	6359
HPRD ID		04243	03232
Ensembl ID		ENSG00000132581	ENSG00000275718
Uniprot IDs		Q6IBU4 Q99470	Q16663
PDB IDs			2HCC 7VL9 7VLA
Enriched GO Terms of Interacting Partners?		CCR Chemokine Receptor Binding Chemokine Activity Chemokine-mediated Signaling Pathway Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Eosinophil Migration Eosinophil Chemotaxis Cell Chemotaxis Cytokine Activity Chemoattractant Activity Humoral Immune Response Positive Chemotaxis Chemotaxis Locomotion Hepatocyte Dedifferentiation Cellular Response To Putrescine Granulocyte Chemotaxis Cytokine-mediated Signaling Pathway Granulocyte Migration Circadian Regulation Of Translation Inflammatory Response Positive Regulation Of Cell Migration Myeloid Leukocyte Migration Positive Regulation Of Cell Motility Leukocyte Chemotaxis Positive Regulation Of Locomotion Cell-cell Signaling Signaling Extracellular Space Somatic Muscle Development Cell Communication Heparin Binding Positive Regulation Of Telomere Capping MCRD-mediated MRNA Stability Complex Response To Rapamycin Cell Dedifferentiation Intracellular Calcium Ion Homeostasis Defense Response To Symbiont Defense Response To Other Organism G Protein-coupled Receptor Signaling Pathway Calcium Ion Homeostasis Response To Sodium Phosphate Minor Groove Of Adenine-thymine-rich DNA Binding Leukocyte Migration Cell Migration CRD-mediated MRNA Stabilization Phospholipase Activator Activity Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Host-mediated Suppression Of Viral Genome Replication Regulation Of Cell Migration	Chemokine-mediated Signaling Pathway Chemokine Receptor Activity Cell Chemotaxis Monocyte Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Chemotaxis Locomotion Cytokine-mediated Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cellular Response To Cytokine Stimulus Inflammatory Response Response To Cytokine Response To Peptide Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Calcium Ion Transport Mononuclear Cell Migration Helper T Cell Extravasation Chemokine (C-C Motif) Ligand 2 Signaling Pathway Leukocyte Chemotaxis Regulation Of Mononuclear Cell Migration Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Myeloid Leukocyte Migration Chemokine (C-C Motif) Ligand 5 Binding Positive Regulation Of Chemotaxis Chemokine (C-C Motif) Ligand 7 Binding Regulation Of Endothelial Cell Proliferation Negative Regulation Of Natural Killer Cell Chemotaxis Cell Adhesion Cell Migration Calcium-mediated Signaling Positive Regulation Of Monoatomic Ion Transport Negative Regulation Of Lymphocyte Chemotaxis Regulation Of Chemotaxis Cell Motility CCR2 Chemokine Receptor Binding Regulation Of Leukocyte Migration Regulation Of Calcium Ion Transport Leukocyte Migration T Cell Extravasation Immune Response Astrocyte Cell Migration Defense Response Positive Regulation Of Apoptotic Cell Clearance Regulation Of Metal Ion Transport External Side Of Plasma Membrane Positive Regulation Of Glutamate Receptor Signaling Pathway
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