FASTKD5 and EBF4

		FASTKD5	EBF4
Description		FAST kinase domains 5	EBF family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule Mitochondrial Nucleoid	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding RRNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding DNA-binding Transcription Factor Binding
	Biological Process	Mitochondrial RNA Processing MRNA Processing Regulation Of Mitochondrial MRNA Stability	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II T Cell Apoptotic Process
Pathways		FASTK family proteins regulate processing and stability of mitochondrial RNAs
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048) Night sleep phenotypes ( 27126917)	Pursuit maintenance gain ( 29064472)
Interacting Genes		6 interacting genes: CCDC85B KCNH1 MID2 MTUS2 RNF10 TRIM27	3 interacting genes: APP CDK6 LNX1
Entrez ID		60493	57593
HPRD ID		07813	13860
Ensembl ID		ENSG00000215251	ENSG00000088881
Uniprot IDs		Q7L8L6	E9PEI2 Q7Z5T1 Q9BQW3
PDB IDs
Enriched GO Terms of Interacting Partners?		Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Negative Regulation Of Viral Process Regulation Of Viral Transcription Regulation Of Viral Process	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Hemopoiesis Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Glial Cell Development Positive Regulation Of G Protein-coupled Receptor Internalization Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex FBXO Family Protein Binding Regulation Of Spontaneous Synaptic Transmission Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Postsynapse Intermediate-density Lipoprotein Particle Developmental Maturation Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Synapse Organization Gliogenesis Negative Regulation Of Monocyte Differentiation Cell Dedifferentiation Axon Choice Point Recognition Regulation Of Mitochondrial MRNA Stability Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion
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