FASTKD5 and SLC24A3

		FASTKD5	SLC24A3
Description		FAST kinase domains 5	solute carrier family 24 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule Mitochondrial Nucleoid	Plasma Membrane Membrane Cell Periphery
	Molecular Function	RNA Binding Protein Binding RRNA Binding	Calcium Channel Activity Calcium, Potassium:sodium Antiporter Activity Symporter Activity Antiporter Activity
	Biological Process	Mitochondrial RNA Processing MRNA Processing Regulation Of Mitochondrial MRNA Stability	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Calcium Ion Transport Intracellular Calcium Ion Homeostasis Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Bone Mineralization Sodium Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport Potassium Ion Transmembrane Transport Transport Across Blood-brain Barrier
Pathways		FASTK family proteins regulate processing and stability of mitochondrial RNAs	Sodium/Calcium exchangers
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048) Night sleep phenotypes ( 27126917)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Body fat mass ( 28224759) Breast cancer and/or colorectal cancer ( 29698419) Cataracts ( 34127677) Cataracts (operation) ( 31816047) Diastolic blood pressure ( 30578418) Diffusing capacity of carbon monoxide ( 30694715) HDL cholesterol ( 31170924) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Matrix metalloproteinase levels ( 20031604) Mean platelet volume ( 27863252 32888494) Metabolite levels ( 23823483) Migraine ( 27182965 27322543) Multisite chronic pain ( 33830993 31194737) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Nicotine dependence symptom count ( 25555482) Plasma parathyroid hormone levels ( 30134803) Platelet count ( 32888494) Psychosis (atypical) ( 24132900) Pulmonary function decline ( 22424883) Pulse pressure ( 30487518 30578418 29403010 28135244 27841878) QT interval (sulfonylurea treatment interaction) ( 27958378) Response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		6 interacting genes: CCDC85B KCNH1 MID2 MTUS2 RNF10 TRIM27
Entrez ID		60493	57419
HPRD ID		07813	15352
Ensembl ID		ENSG00000215251	ENSG00000185052
Uniprot IDs		Q7L8L6	Q9HC58
PDB IDs
Enriched GO Terms of Interacting Partners?		Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Negative Regulation Of Viral Process Regulation Of Viral Transcription Regulation Of Viral Process	Ribonucleoprotein Granule Regulation Of Mitochondrial MRNA Stability Mitochondrial RNA Processing Mitochondrial Nucleoid RRNA Binding
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