BRINP2 and TBX19

		BRINP2	TBX19
Description		BMP/retinoic acid inducible neural specific 2	T-box transcription factor 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Dendrite Neuronal Cell Body	Chromatin Nucleus
	Molecular Function		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Nervous System Development Central Nervous System Neuron Differentiation Multicellular Organism Growth Locomotion Positive Regulation Of Neuron Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Cellular Response To Retinoic Acid	Mesoderm Formation Cell Fate Specification Heart Morphogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Pituitary Gland Development Regulation Of Cell Population Proliferation Cell Fate Commitment Regulation Of Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases			Adrenocorticotropic hormone deficiency; Isolated ACDH deficiency (IAD)
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body composition traits ( 30026463) Schizophrenia ( 29483656)
Interacting Genes			15 interacting genes: GCM2 HGS HOXC8 IRX6 LONRF1 NEDD9 NR5A1 PITX1 POGZ PRR35 RAB2B TBX6 TFG VENTX ZIC1
Entrez ID		57795	9095
HPRD ID		13891	05214
Ensembl ID		ENSG00000198797	ENSG00000143178
Uniprot IDs		Q9C0B6	B3KRD9 O60806
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K33-linked Ubiquitination Type II Interferon Binding	Sequence-specific Double-stranded DNA Binding Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Biosynthetic Process DNA Binding Positive Regulation Of Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cellular Developmental Process Positive Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Neuron Differentiation DNA-binding Transcription Factor Activity Cell Differentiation Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Immunological Synapse Formation Regulation Of Primary Metabolic Process Negative Regulation Of Female Gonad Development Primary Sex Determination Regulation Of RNA Metabolic Process Gland Development Regulation Of Metabolic Process Branchiomeric Skeletal Muscle Development Myoblast Fate Commitment Negative Regulation Of Neuron Maturation ESCRT-0 Complex Positive Regulation Of Exocytosis
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