SLC44A2 and IQCN

		SLC44A2	IQCN
Description		solute carrier family 44 member 2 (CTL2 blood group)	IQ motif containing N
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Lysosomal Membrane Plasma Membrane Membrane Specific Granule Membrane Extracellular Exosome	Nucleus Mitochondrion
	Molecular Function	Choline Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity Ethanolamine Transmembrane Transporter Activity	Protein Binding
	Biological Process	Phosphatidylcholine Biosynthetic Process Choline Transport Ethanolamine Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction Transmembrane Transport	Spermatid Development
Pathways		Synthesis of PC Neutrophil degranulation SLC-mediated bile acid transport
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Bipolar disorder ( 31043756) Height ( 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 24076602) Platelet count ( 29403010 32888494) Platelet distribution width ( 27863252 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Thrombosis ( 26908601) Venous thromboembolism ( 31676865 25772935)	Visceral adipose tissue volume ( 34128465)
Interacting Genes		2 interacting genes: BDKRB1 HTR2B	14 interacting genes: CALM1 CALM2 CALM3 CALML3 CYSRT1 LINC00839 LZTS2 MID2 PLSCR1 PUF60 RBM17 SIAH1 TRIM27 TRIP6
Entrez ID		57153	80726
HPRD ID		16198	13882
Ensembl ID		ENSG00000129353	ENSG00000130518
Uniprot IDs		A0A088QCU6 Q8IWA5	A0JP07 Q9H0B3
PDB IDs
Enriched GO Terms of Interacting Partners?		Phylloquinone Catabolic Process Menaquinone Metabolic Process Menaquinone Catabolic Process Vitamin K Catabolic Process Vitamin K Metabolic Process Ketone Catabolic Process Vitamin Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Regulation Of Biological Quality Arachidonate Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Monooxygenase Activity Ketone Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Icosanoid Metabolic Process Bradykinin Receptor Activity Oxylipin Biosynthetic Process Iron Ion Binding Heme Binding Regulation Of Sequestering Of Calcium Ion Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process Olefinic Compound Metabolic Process Pressure Natriuresis G Protein-coupled Serotonin Receptor Complex Intestine Smooth Muscle Contraction Arachidonate Omega-hydroxylase Activity Cytochrome Metabolic Process Leukotriene B4 Catabolic Process Leukotriene B4 Metabolic Process Leukotriene-B4 20-monooxygenase Activity Alkane 1-monooxygenase Activity Vitamin E Metabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Positive Regulation Of Nuclear Cell Cycle DNA Replication Phospholipase C-activating Serotonin Receptor Signaling Pathway Long-chain Fatty Acid Catabolic Process Serotonin Binding Serotonin Receptor Signaling Pathway Omega-hydroxylase P450 Pathway Arachidonate Epoxygenase Activity Positive Regulation Of Phospholipid Biosynthetic Process Serotonin Receptor Activity Neural Crest Cell Differentiation GTPase Inhibitor Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen G Protein-coupled Serotonin Receptor Activity Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Body Fluid Levels	Detection Of Calcium Ion Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Calcineurin-mediated Signaling Myelin Sheath Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Presynaptic Cytosol Detection Of Chemical Stimulus Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Calcium Ion Transmembrane Transport Synaptic Vesicle Membrane Response To Calcium Ion Presynaptic Endocytosis Spindle Microtubule Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Substantia Nigra Development Regulation Of Calcium Ion Transmembrane Transport Response To Metal Ion Calcium Channel Regulator Activity Sperm Midpiece Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Calcium-mediated Signaling Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Positive Regulation Of Sequestering Of Calcium Ion Vesicle Sarcomere Cell Cycle G2/M Phase Transition Negative Regulation Of Voltage-gated Calcium Channel Activity Neural Nucleus Development Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Calcium Ion Transport
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