SLC44A2 and CDC42SE1

		SLC44A2	CDC42SE1
Description		solute carrier family 44 member 2 (CTL2 blood group)	CDC42 small effector 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Lysosomal Membrane Plasma Membrane Membrane Specific Granule Membrane Extracellular Exosome	Cytoplasm Cytoskeleton Plasma Membrane Membrane Cell Junction
	Molecular Function	Choline Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity Ethanolamine Transmembrane Transporter Activity	GTPase Inhibitor Activity Protein Binding Small GTPase Binding
	Biological Process	Phosphatidylcholine Biosynthetic Process Choline Transport Ethanolamine Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction Transmembrane Transport	Phagocytosis Signal Transduction Regulation Of Cell Shape Regulation Of Rho Protein Signal Transduction
Pathways		Synthesis of PC Neutrophil degranulation SLC-mediated bile acid transport
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Bipolar disorder ( 31043756) Height ( 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 24076602) Platelet count ( 29403010 32888494) Platelet distribution width ( 27863252 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Thrombosis ( 26908601) Venous thromboembolism ( 31676865 25772935)
Interacting Genes		2 interacting genes: BDKRB1 HTR2B	4 interacting genes: CDC42 DAPK1 RAC1 SNCA
Entrez ID		57153	56882
HPRD ID		16198	16694
Ensembl ID		ENSG00000129353	ENSG00000197622
Uniprot IDs		A0A088QCU6 Q8IWA5	Q9NRR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Phylloquinone Catabolic Process Menaquinone Metabolic Process Menaquinone Catabolic Process Vitamin K Catabolic Process Vitamin K Metabolic Process Ketone Catabolic Process Vitamin Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Regulation Of Biological Quality Arachidonate Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Monooxygenase Activity Ketone Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Icosanoid Metabolic Process Bradykinin Receptor Activity Oxylipin Biosynthetic Process Iron Ion Binding Heme Binding Regulation Of Sequestering Of Calcium Ion Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process Olefinic Compound Metabolic Process Pressure Natriuresis G Protein-coupled Serotonin Receptor Complex Intestine Smooth Muscle Contraction Arachidonate Omega-hydroxylase Activity Cytochrome Metabolic Process Leukotriene B4 Catabolic Process Leukotriene B4 Metabolic Process Leukotriene-B4 20-monooxygenase Activity Alkane 1-monooxygenase Activity Vitamin E Metabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Positive Regulation Of Nuclear Cell Cycle DNA Replication Phospholipase C-activating Serotonin Receptor Signaling Pathway Long-chain Fatty Acid Catabolic Process Serotonin Binding Serotonin Receptor Signaling Pathway Omega-hydroxylase P450 Pathway Arachidonate Epoxygenase Activity Positive Regulation Of Phospholipid Biosynthetic Process Serotonin Receptor Activity Neural Crest Cell Differentiation GTPase Inhibitor Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen G Protein-coupled Serotonin Receptor Activity Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Body Fluid Levels	Thioesterase Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Response To Type II Interferon Regulation Of Hydrogen Peroxide Metabolic Process GTP-dependent Protein Binding Positive Regulation Of Lamellipodium Organization Positive Regulation Of Lamellipodium Assembly Wnt Signaling Pathway, Planar Cell Polarity Pathway Phagocytosis, Engulfment Postsynapse Regulation Of Synaptic Vesicle Recycling Cell Projection Morphogenesis Regulation Of Signal Transduction Positive Regulation Of Stress Fiber Assembly Regulation Of Lamellipodium Organization Regulation Of Lamellipodium Assembly Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Membrane Invagination Regulation Of Synapse Organization Non-canonical Wnt Signaling Pathway Regulation Of Endocytosis Lamellipodium Organization Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Neuronal Synaptic Plasticity Regulation Of Cell Communication GTP Binding Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Signaling Regulation Of Supramolecular Fiber Organization Cellular Response To Type II Interferon Positive Regulation Of Actin Filament Bundle Assembly G Protein Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Regulation Of Microtubule Polymerization Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Cytoplasmic Ribonucleoprotein Granule Regulation Of Protein-containing Complex Assembly Positive Regulation Of Intracellular Signal Transduction Endocytosis Regulation Of Stress Fiber Assembly GBD Domain Binding Storage Vacuole Positive Regulation Of Organelle Organization Cell Junction Organization
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