DTWD1 and SLC27A2

		DTWD1	SLC27A2
Description		DTW motif tRNA-uridine aminocarboxypropyltransferase 1	solute carrier family 27 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	TRNA-uridine Aminocarboxypropyltransferase Activity Transferase Activity	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transmembrane Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Ligase Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity
	Biological Process	TRNA Modification TRNA Processing	Very Long-chain Fatty Acid Metabolic Process Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Lipid Transport Bile Acid Metabolic Process Fatty Acid Transport Long-chain Fatty Acid Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Very Long-chain Fatty Acid Catabolic Process Long-chain Fatty Acid Import Into Cell Fatty-acyl-CoA Biosynthetic Process Methyl-branched Fatty Acid Metabolic Process
Pathways			Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Beta-oxidation of very long chain fatty acids Neutrophil degranulation Fatty acyl-CoA biosynthesis Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Response to anti-depressant treatment in major depressive disorder ( 22041458)	Platelet count ( 32888494) Verbal declarative memory ( 25648963)
Interacting Genes		2 interacting genes: APP DAPK1	4 interacting genes: ABCD1 PEX5 UBC YWHAQ
Entrez ID		56986	11001
HPRD ID		17474	11935
Ensembl ID		ENSG00000104047	ENSG00000140284
Uniprot IDs		Q8N5C7	O14975
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Endoplasmic Reticulum Lumen Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Pristanate-CoA Ligase Activity Phytanate-CoA Ligase Activity Methyl-branched Fatty Acid Metabolic Process Cholate-CoA Ligase Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Fatty Acid Transmembrane Transporter Activity Very Long-chain Fatty Acid Catabolic Process Fatty Acid Alpha-oxidation Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Enzyme Binding Cellular Response To Manganese Ion Cellular Response To Hydroperoxide Regulation Of Translation	Protein Targeting
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