TMEM126B and NARS2

		TMEM126B	NARS2
Description		transmembrane protein 126B	asparaginyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding	Nucleotide Binding Nucleic Acid Binding Aminoacyl-tRNA Ligase Activity Asparagine-tRNA Ligase Activity ATP Binding Ligase Activity
	Biological Process	Mitochondrion Organization Response To Food Mitochondrial Respiratory Chain Complex I Assembly	Translation TRNA Aminoacylation For Protein Translation Asparaginyl-tRNA Aminoacylation
Pathways		Complex I biogenesis	Mitochondrial tRNA aminoacylation
Drugs			Asparagine
Diseases
GWAS		Height ( 19570815) Metabolite levels ( 23823483)	Alzheimer's disease (survival time) ( 25649651) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Estimated glomerular filtration rate ( 31451708) High light scatter reticulocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Tourette syndrome ( 30818990) Verbal declarative memory ( 25648963)
Interacting Genes		3 interacting genes: APP MRFAP1L1 UBC
Entrez ID		55863	79731
HPRD ID		13715	08026
Ensembl ID		ENSG00000171204	ENSG00000137513
Uniprot IDs		Q8IUX1	A0A8Q3SHL5 A0A8Q3SHT7 A0A8Q3WKF4 B3KPX5 H0YE96 Q96I59 Q9H5H1
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Regulation Of Nervous System Process Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cardiac Cell Fate Specification Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity Asparagine-tRNA Ligase Activity Asparaginyl-tRNA Aminoacylation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Central Nervous System Myelin Formation Axon Choice Point Recognition Positive Regulation Of Gastrulation Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion	Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity
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