PIGV and PITHD1

		PIGV	PITHD1
Description		phosphatidylinositol glycan anchor biosynthesis class V	PITH domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mannosyltransferase Complex	Nucleus Cytoplasm Sperm Cytoplasmic Droplet
	Molecular Function	Alpha-1,6-mannosyltransferase Activity Mannosyltransferase Activity GPI Mannosyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process	Spermatid Development Penetration Of Zona Pellucida Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Penetration Of Cumulus Oophorus Regulation Of Primary Metabolic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Blond vs. brown/black hair color ( 30531825) Blood protein levels in cardiovascular risk ( 28369058) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) LDL cholesterol ( 24097068 25961943) LDL cholesterol levels ( 28334899) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 27863252) Sum basophil neutrophil counts ( 27863252) Triglyceride levels ( 28334899 32154731) Triglycerides ( 24097068)	High light scatter reticulocyte percentage of red cells ( 27863252)
Interacting Genes			3 interacting genes: CDC73 HUNK SUMO4
Entrez ID		55650	57095
HPRD ID		07912	13717
Ensembl ID		ENSG00000060642	ENSG00000057757
Uniprot IDs		A0A6I8PU65 A0A8I5KQ29 A0A8I5KRV8 Q9NUD9	B4DKP7 Q9GZP4
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Penetration Of Cumulus Oophorus
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