GIMAP4 and CHPF2

		GIMAP4	CHPF2
Description		GTPase, IMAP family member 4	chondroitin polymerizing factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Nucleotide Binding GTPase Activity GTP Binding	Acetylgalactosaminyltransferase Activity Transferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity
	Biological Process		Chondroitin Sulfate Proteoglycan Biosynthetic Process
Pathways			CS-GAG biosynthesis
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Triglyceride levels ( 32203549) vWF levels ( 30586737)	Eyebrow thickness ( 26926045) Multiple myeloma ( 27363682)
Interacting Genes		3 interacting genes: APP CFTR RBFOX2
Entrez ID		55303	54480
HPRD ID		16281	10474
Ensembl ID		ENSG00000133574	ENSG00000033100
Uniprot IDs		A0A090N7X0 G5E9W9 Q9NUV9	A0A8I5KRN5 B3KPG6 C9JZF7 G5E9W2 Q9P2E5
PDB IDs		3LXX
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Recycling Endosome Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Developmental Maturation Early Endosome Membrane Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Transepithelial Water Transport Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Positive Regulation Of Protein Transport Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Tooth Mineralization	Negative Regulation Of Dendritic Cell Differentiation Regulation Of Dendritic Cell Differentiation
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