ZNF532 and ALPK2

		ZNF532	ALPK2
Description		zinc finger protein 532	alpha kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Zinc Ion Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Regulation Of DNA-templated Transcription	Heart Morphogenesis Negative Regulation Of Wnt Signaling Pathway Involved In Heart Development Regulation Of Gene Expression Establishment Of Cell Polarity Regulation Of Apoptotic Process Cardiac Muscle Cell Development Epicardium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Staphylococcus aureus nasal carriage (intermittent) ( 26569114) Triptolide cytotoxicity ( 26121980)	Alanine aminotransferase levels ( 33547301) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Diisocyanate-induced asthma ( 25918132) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Family history of Alzheimer's disease ( 30617256) HDL cholesterol levels ( 32203549) Hip circumference ( 28552196) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 21833088) Multiple sclerosis and systolic blood pressure (pleiotropy) ( 26920376) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549 32154731)
Interacting Genes		5 interacting genes: BTG3 ERBB2 ERBB3 ERBB4 KPNA4
Entrez ID		55205	115701
HPRD ID		11724	11019
Ensembl ID		ENSG00000074657	ENSG00000198796
Uniprot IDs		B3KXW2 Q9HCE3	Q86TB3
PDB IDs
Enriched GO Terms of Interacting Partners?		ERBB2 Signaling Pathway ERBB3:ERBB2 Complex Neuregulin Receptor Activity ErbB-3 Class Receptor Binding Basal Plasma Membrane ERBB2-ERBB4 Signaling Pathway Basolateral Plasma Membrane Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Protein Tyrosine Kinase Activity Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Kinase Activity Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Peripheral Nervous System Development Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Heart Development Growth Factor Binding Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Response To Epidermal Growth Factor Receptor Localization To Synapse Neuron Differentiation Protein Localization To Synapse Regulation Of Epithelial Cell Proliferation Glial Cell Development Protein-containing Complex Localization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Intracellular Signal Transduction Wound Healing Protein Localization To Cell Junction Positive Regulation Of MAPK Cascade Neuromuscular Junction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Planar Polarity Involved In Nephron Morphogenesis Negative Regulation Of Wnt Signaling Pathway Involved In Heart Development Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Myelination Protein Kinase Activity Axon Ensheathment ATP Binding Glial Cell Differentiation Regulation Of Apoptotic Process Regulation Of Programmed Cell Death
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