CHPF2 and GIMAP4

		CHPF2	GIMAP4
Description		chondroitin polymerizing factor 2	GTPase, IMAP family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane	Cytoplasm Cytosol
	Molecular Function	Acetylgalactosaminyltransferase Activity Transferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity	Nucleotide Binding GTPase Activity GTP Binding
	Biological Process	Chondroitin Sulfate Proteoglycan Biosynthetic Process
Pathways		CS-GAG biosynthesis
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Multiple myeloma ( 27363682)	Eosinophil percentage of white cells ( 32888494) Triglyceride levels ( 32203549) vWF levels ( 30586737)
Interacting Genes			3 interacting genes: APP CFTR RBFOX2
Entrez ID		54480	55303
HPRD ID		10474	16281
Ensembl ID		ENSG00000033100	ENSG00000133574
Uniprot IDs		A0A8I5KRN5 B3KPG6 C9JZF7 G5E9W2 Q9P2E5	A0A090N7X0 G5E9W9 Q9NUV9
PDB IDs			3LXX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Dendritic Cell Differentiation Regulation Of Dendritic Cell Differentiation	Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Recycling Endosome Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Developmental Maturation Early Endosome Membrane Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Transepithelial Water Transport Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Positive Regulation Of Protein Transport Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Tooth Mineralization
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