CHPF2 and TMEM176B

		CHPF2	TMEM176B
Description		chondroitin polymerizing factor 2	transmembrane protein 176B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane	Nucleus Membrane Nuclear Membrane
	Molecular Function	Acetylgalactosaminyltransferase Activity Transferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity	Protein Binding
	Biological Process	Chondroitin Sulfate Proteoglycan Biosynthetic Process	Animal Organ Morphogenesis Cell Differentiation Dendritic Cell Differentiation Negative Regulation Of Dendritic Cell Differentiation
Pathways		CS-GAG biosynthesis
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Multiple myeloma ( 27363682)	Appendicular lean mass ( 33097823) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693)
Interacting Genes			3 interacting genes: GLP1R SLC22A2 TMEM176A
Entrez ID		54480	28959
HPRD ID		10474	17443
Ensembl ID		ENSG00000033100	ENSG00000106565
Uniprot IDs		A0A8I5KRN5 B3KPG6 C9JZF7 G5E9W2 Q9P2E5	A0A090N7V7 Q3YBM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Dendritic Cell Differentiation Regulation Of Dendritic Cell Differentiation	Response To Psychosocial Stress Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity Acetylcholine Transport Histamine Uptake Pyrimidine Nucleoside Transmembrane Transporter Activity Spermidine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Amine Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Spermidine Transmembrane Transporter Activity L-arginine Import Across Plasma Membrane Putrescine Transmembrane Transporter Activity Thiamine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity Post-translational Protein Targeting To Membrane, Translocation Serotonin Uptake Choline Transport Norepinephrine Uptake Prostaglandin Transmembrane Transporter Activity Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Choline Transmembrane Transporter Activity Norepinephrine Transport Polyamine Transmembrane Transport Histamine Transport L-arginine Transmembrane Transporter Activity Acetylgalactosaminyltransferase Activity Negative Regulation Of Dendritic Cell Differentiation Cellular Response To Glucagon Stimulus Organic Cation Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity L-arginine Transmembrane Transport Amine Transport Catecholamine Uptake Dopamine Uptake Activation Of Adenylate Cyclase Activity Azole Transmembrane Transport Quaternary Ammonium Group Transport Prostaglandin Transport Serotonin Transport Pyrimidine-containing Compound Transmembrane Transport L-amino Acid Transmembrane Transporter Activity
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