LGSN and MTCH1

		LGSN	MTCH1
Description		lengsin, lens protein with glutamine synthetase domain	mitochondrial carrier 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Catalytic Activity Glutamine Synthetase Activity	Protein Binding Membrane Insertase Activity
	Biological Process	Glutamine Biosynthetic Process Nitrogen Utilization	Apoptotic Process Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Outer Membrane Neuronal Ion Channel Clustering
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Asthma ( 34103634) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Obesity-related traits ( 23251661)	Acne (severe) ( 24927181) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
Interacting Genes			5 interacting genes: APLNR ERBB2 GSK3A PSEN1 UBC
Entrez ID		51557	23787
HPRD ID		13585	14787
Ensembl ID		ENSG00000146166	ENSG00000137409
Uniprot IDs		Q5TDP6	A0A8Q3WKC8 A8YXX5 H0Y8C3 Q9NZJ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuronal Ion Channel Clustering Membrane Insertase Activity Protein Insertion Into Mitochondrial Outer Membrane Establishment Of Protein Localization To Mitochondrial Membrane Protein Insertion Into Mitochondrial Membrane Establishment Of Protein Localization To Mitochondrion Protein Insertion Into Membrane Mitochondrial Membrane Organization Establishment Of Protein Localization To Membrane Mitochondrial Outer Membrane	Heart Development Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Muscle Hypertrophy Mechanoreceptor Activity Apelin Receptor Activity Heart Looping Embryonic Heart Tube Morphogenesis Regulation Of Cardiac Muscle Hypertrophy Apelin Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Hypertrophy Calcium-dependent ATPase Activity Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Apoptotic Signaling Pathway ERBB3:ERBB2 Complex Neuromuscular Junction Negative Regulation Of Cell Development Positive Regulation Of Establishment Of Protein Localization Negative Regulation Of UDP-glucose Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Regulation Of Carbohydrate Catabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Quinone Catabolic Process Melatonin Binding Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Dihydronicotinamide Riboside Quinone Reductase Activity Resveratrol Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cajal-Retzius Cell Differentiation Negative Regulation Of Core Promoter Binding Glutamine Synthetase Activity Glutamine Biosynthetic Process Nitrogen Utilization Positive Regulation Of G Protein-coupled Receptor Internalization RNA Polymerase I Core Binding NAD(P)H Dehydrogenase (quinone) Activity Protein Catabolic Process At Postsynapse Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Epithelial Tube Morphogenesis Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Synaptic Vesicle Targeting Astrocyte Activation Involved In Immune Response
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